Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169416 | 0.71 | MAPK1 (0.38) | KDM4EKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL4728473 | 0.69 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL30061301 | 0.67 | — | — | |
| SCHEMBL30641570 | 0.67 | KDM4E (0.40) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7093049 | 0.67 | ADORA2A (0.45) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL32810 | 0.66 | KDM4E (0.46) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9279667 | 0.64 | KDM4E (0.37) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL952863 | 0.64 | NOTUM (0.48) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL27869303 | 0.64 | — | — | |
| SCHEMBL30297917 | 0.63 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 894 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584740-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-02-21 | — | — | US | claimed |
| US-20180277777-A1 | Tridentate Cyclometalated Metal Complexes with Six-Membered Coordination Rings | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-09-27 | — | — | US | claimed |
| US-20170125708-A1 | Tridentate Cyclometalated Metal Complexes with Six-Membered Coordination Rings | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2017-05-04 | — | — | US | claimed |
| US-9562038-B2 | Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus | YALE UNIVERSITY (US) | 2017-02-07 | — | — | US | claimed |
| US-20160028029-A1 | Tridentate Cyclometalated Metal Complexes with Six-Membered Coordination Rings | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2016-01-28 | — | — | US | claimed |
| CN-103224488-A | Heterocyclic compound or salt thereof | OTSUKA PHARMA CO LTD | 2013-07-31 | — | — | CN | claimed |
| CN-103221397-A | Novel compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC | 2013-07-24 | — | — | CN | claimed |
| US-8492362-B1 | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-varicella zoster virus agents and methods of use | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-07-23 | — | — | US | claimed |
| CN-103068828-A | Triazolopyrazine derivatives | MERCK PATENT GMBH | 2013-04-24 | — | — | CN | claimed |
| CN-103052640-A | Furopyridine derivatives | MERCK PATENT GMBH | 2013-04-17 | — | — | CN | claimed |
| CN-1283191-A | Benzylidene pyrazolones, preparation and use thereof | BASF AG (DE) | 2001-02-07 | — | — | CN | claimed |
| CN-1249749-A | Phthalazinones | BYK GULDEN LOMBERC CHEM FAB GM (DE) | 2000-04-05 | — | — | CN | claimed |
| CN-1145075-A | Antagonist's of endothelin receptors | JAPAT LTD (CH) | 1997-03-12 | — | — | CN | claimed |
| CN-1112125-A | Acyloxyhexanoic acid derivatives | CIBA GEIGY AG (CH) | 1995-11-22 | — | — | CN | claimed |
| CN-1108955-A | The use of compositions for combating tumour diseases | CIBA GEIGY AG (CH) | 1995-09-27 | — | — | CN | claimed |
| CN-1093701-A | Antiretroviral hydrazine derivative | CIBA GEIGY AG (CH) | 1994-10-19 | — | — | CN | claimed |
| CN-1089269-A | Novel 5-amino-4-hydroxy caproic acid derivative as therapeutical agent | CIBA GEIGY AG (CH) | 1994-07-13 | — | — | CN | claimed |
| US-5215983-A | Useful for treatment of infectious diseases in a human as well as animal | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | claimed |
| EP-0281098-B1 | BENZODIOXOLE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME, AND THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS | Eisai Co., Ltd. (JP) | 1992-11-25 | — | — | EP | claimed |
| EP-0424832-A2 | Carbapenem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160028029-A1 | Tridentate Cyclometalated Metal Complexes with Six-Membered Coordination Rings | CRY1, SOD1, INTS6 | KDM4E 3082/4885ALDH1A1 1483/4885LMNA 4422/4885 |
| US-20180277777-A1 | Tridentate Cyclometalated Metal Complexes with Six-Membered Coordination Rings | CRY1, SOD1, INTS6 | KDM4E 3082/4885ALDH1A1 1483/4885LMNA 4422/4885 |
| US-20170125708-A1 | Tridentate Cyclometalated Metal Complexes with Six-Membered Coordination Rings | CRY1, SOD1, INTS6 | KDM4E 3082/4885ALDH1A1 1483/4885LMNA 4422/4885 |
| US-11584740-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | IFNG, TLR1, IDO1 | KDM4E 1828/4885ALDH1A1 1059/4885LMNA 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.