Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP1 | O94782 | 5/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451920 | 0.77 | NPSR1 (0.46) | GAAMAPTMEN1KMT2ANTRK1 | |
| SCHEMBL2446363 | 0.76 | AAK1 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C19RECQL | |
| SCHEMBL14472097 | 0.73 | PARP1 (0.38) | CYP1A2CYP3A4CYP2D6TSHRCRHR1 | |
| SCHEMBL2442498 | 0.72 | DPP4 (0.40) | CYP1A2CYP3A4CYP2D6TSHRCRHR1 | |
| SCHEMBL2451004 | 0.71 | WDR5 (0.41) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL18939276 | 0.69 | HTT (0.56) | TSHRSMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL904650 | 0.67 | LDHA (0.46) | CYP1A2CYP3A4CYP2D6TSHRCRHR1 | |
| SCHEMBL14941196 | 0.65 | LDHA (0.41) | CRHR1SMN1; SMN2MAPTMEN1HTT | |
| SCHEMBL805590 | 0.63 | HSD11B1 (0.51) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL802782 | 0.62 | GSK3A (0.46) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109587-A1 | SUBSTITUTED AZA-BICYCLIC IMIDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-09-09 | — | — | WO | disclosed |