SCHEMBL2187669

SCHEMBL2187669

Cc1ccc(-c2cc(C)c(-c3ccc(C)cc3)cn2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.46
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
METAP2 P50579 1/20 0.41
METAP1 P53582 1/20 0.41
KDM1A O60341 1/20 0.40
TGFBR1 P36897 1/20 0.39
KDM4E B2RXH2 5/20 0.39
HPGD P15428 4/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
ALDH1A1 P00352 2/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KMT2A Q03164 3/20 0.38
PPARG P37231 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19454861 0.93 LDHA (0.57) LDHATGFBR1KDM4EHPGDNPC1
SCHEMBL25029628 0.87 LDHA (0.42) LDHACCR1CCR5CCR8HDAC6
SCHEMBL29604379 0.84 LDHA (0.64) LDHAKDM4ENPC1RAB9AALDH1A1
SCHEMBL117744 0.84 LDHA (0.64) LDHAKDM4ENPC1RAB9AALDH1A1
SCHEMBL21202790 0.84 LDHA (0.51) LDHATGFBR1KDM4EHPGDNPC1
SCHEMBL18729621 0.83 CCR1 (0.44) LDHACCR1CCR5CCR8HDAC6
SCHEMBL14988841 0.82 LDHA (0.62) LDHAKDM4ENPC1RAB9AALDH1A1
SCHEMBL29365185 0.82 LDHA (0.62) LDHAKDM4ENPC1RAB9AALDH1A1
SCHEMBL21468869 0.79 KDM4E (0.50) LDHATGFBR1KDM4EHPGDNPC1
SCHEMBL21202809 0.79 LDHA (0.54) LDHAKDM4EHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 EP disclosed
EP-3399005-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2023-05-31 EP disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 US disclosed
US-11482685-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-10-25 US disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 US disclosed
US-10892426-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-01-12 US disclosed
US-20200152890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-14 US disclosed
US-10593896-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-17 US disclosed
US-20190148651-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-16 US disclosed
US-20170194577-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-07-06 US disclosed
US-9630983-B2 Organic electroluminescent material and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-04-25 US disclosed
US-20150307535-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2015-10-29 US disclosed
US-9076973-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2015-07-07 US disclosed
US-20140021449-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2014-01-23 US disclosed
US-8519384-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2013-08-27 US disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 US disclosed
EP-2342305-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2011-07-13 EP disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200152890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, LMNB2, RUVBL2 LDHA 42/4885CCR1 2299/4885CCR5 2410/4885
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM LDHA 163/4885CCR1 1965/4885CCR5 1610/4885
US-10892426-B2 Organic electroluminescent materials and devices OCIAD2, LMNB2, RUVBL2 LDHA 42/4885CCR1 2299/4885CCR5 2410/4885
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, MCM4, KCNMB4 LDHA 207/4885CCR1 2336/4885CCR5 1538/4885
US-20190148651-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, DDT, EML4 LDHA 388/4885CCR1 1754/4885CCR5 1235/4885
US-20110227049-A1 PHOSPHORESCENT MATERIALS PPIP5K2, PAICS, IP6K1 LDHA 1478/4885CCR1 2631/4885CCR5 2273/4885
US-11482685-B2 Organic electroluminescent materials and devices EML4, MCM4, KCNMB4 LDHA 207/4885CCR1 2336/4885CCR5 1538/4885
US-10593896-B2 Organic electroluminescent materials and devices TYR, DDT, EML4 LDHA 388/4885CCR1 1754/4885CCR5 1235/4885
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CLTB, L1CAM LDHA 163/4885CCR1 1965/4885CCR5 1610/4885
US-20170194577-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, DDT, EML4 LDHA 388/4885CCR1 1754/4885CCR5 1235/4885
US-20150307535-A1 PHOSPHORESCENT MATERIALS PPIP5K2, PAICS, IP6K1 LDHA 1478/4885CCR1 2631/4885CCR5 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.