SCHEMBL25755553

SCHEMBL25755553

Cc1cnc(-c2ccc(F)cc2)cc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 2/20 0.45
IDO1 P14902 1/20 0.45
NPC1 O15118 3/20 0.43
RXFP1 Q9HBX9 1/20 0.43
MAPK14 Q16539 2/20 0.42
LDHA P00338 1/20 0.42
AURKA O14965 1/20 0.42
ABL1 P00519 1/20 0.42
NTRK1 P04629 1/20 0.42
LCK P06239 1/20 0.42
CSF1R P07333 1/20 0.42
RET P07949 1/20 0.42
MET P08581 1/20 0.42
PDGFRB P09619 1/20 0.42
PIM1 P11309 1/20 0.42
PDGFRA P16234 1/20 0.42
FLT3 P36888 1/20 0.42
MAPK8 P45983 1/20 0.42
CDK8 P49336 1/20 0.42
MAP2K1 Q02750 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26532553 0.86 ABL1 (0.43) TDO2IDO1NPC1MAPK14ABL1
SCHEMBL18729621 0.83 CCR1 (0.44) NPC1MAPK14LDHAAURKAABL1
SCHEMBL30197384 0.83 TDO2 (0.42) TDO2IDO1NPC1RXFP1MAPK14
SCHEMBL21290369 0.83 TDO2 (0.42) TDO2IDO1NPC1RXFP1MAPK14
SCHEMBL30585411 0.83 TDO2 (0.42) TDO2IDO1NPC1RXFP1MAPK14
SCHEMBL19454849 0.80 LDHA (0.59) TDO2IDO1NPC1LDHAPDGFRB
SCHEMBL29507311 0.79 LDHA (0.62) TDO2IDO1NPC1LDHAPDGFRB
SCHEMBL22080310 0.79 NPC1 (0.53) NPC1LDHANOS3NOS1NOS2
SCHEMBL2481915 0.79 LDHA (0.62) TDO2IDO1NPC1LDHAPDGFRB
SCHEMBL22699338 0.78 LDHA (0.53) NPC1LDHAPDGFRBFLT3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LBR TDO2 3580/4885IDO1 2660/4885NPC1 1803/4885
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LOXL1, OCIAD2, OGFRL1 TDO2 2667/4885IDO1 644/4885NPC1 684/4885
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, RUVBL2, LBR TDO2 3096/4885IDO1 1908/4885NPC1 2419/4885
US-20230337520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, LPO, LPL TDO2 3755/4885IDO1 1354/4885NPC1 1845/4885
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OPRM1, OSBP TDO2 3255/4885IDO1 1162/4885NPC1 608/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 TDO2 3882/4885IDO1 3667/4885NPC1 4515/4885
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRM1, CHRM1 TDO2 3064/4885IDO1 728/4885NPC1 2026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.