Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17360706 | 0.86 | MAPT (0.33) | HTR2AHRH1TRPV1TRPA1MAPT | |
| SCHEMBL10542932 | 0.78 | — | — | |
| SCHEMBL272638 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRHTR2AHRH1HRH4 | |
| SCHEMBL11328208 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRHTR2AHRH1TRPV1 | |
| SCHEMBL22894143 | 0.75 | — | — | |
| SCHEMBL557310 | 0.75 | — | — | |
| SCHEMBL1674533 | 0.75 | — | — | |
| SCHEMBL21164180 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TSHRHTR2AHRH1TDP1 | |
| Hydrochloric Acid SCHEMBL11562089 | 0.73 | OPRM1 (0.46) | ALDH1A1TSHRHTR2AHRH1HRH4 | |
| SCHEMBL1313423 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016037946-A1 | STABLE DEFOAMERS FOR HIGH ELECTROLYTE AGRICULTURAL FORMULATIONS | WACKER CHEMIE AG (DE) | 2016-03-17 | — | — | WO | disclosed |
| US-20160066567-A1 | STABLE DEFOAMERS FOR HIGH ELECTROLYTE AGRICULTURAL FORMULATIONS | WACKER CHEMICAL CORPORATION | 2016-03-10 | — | — | US | disclosed |
| US-8986647-B2 | Hydrophilic silicone copolymers useful in carbon fiber production | WACKER CHEMICAL CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |
| US-20130101494-A1 | Hydrophilic Silicone Copolymers Useful In Carbon Fiber Production | WACKER CHEMICAL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| US-8084566-B2 | Antifoaming compositions | WACKER CHEMIE AG (DE) | 2011-12-27 | — | — | US | disclosed |
| US-20110218137-A1 | ANTIFOAMING COMPOSITIONS | WACKER CHEMIE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| US-7645360-B2 | Defoamer formulations | WACKER CHEMIE AG (DE) | 2010-01-12 | — | — | US | disclosed |
| US-20080200608-A1 | Defoamer Formulations | WACKER CHEMIE AG (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080075683-A1 | Method for Modifying Fibrous Substrates with Siloxan Copolymers | WACKER CHEMIE AG (DE) | 2008-03-27 | — | — | US | disclosed |
| US-7319120-B2 | Hydrosilylating Si H-functional organosiloxane with compound containing hydrosilylatable group and active hydrogen (allylpolyoxyalkylene alcohol); reacting intermediate with di- or polyisocyanate; reactants contain less than 2000 ppm water | WACKER CHEMIE AG (DE) | 2008-01-15 | — | — | US | disclosed |
| US-20060155051-A1 | Hydrophilic copolysiloxanes and method for the production thereof | WACKER-CHEMIE GMBH (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160066567-A1 | STABLE DEFOAMERS FOR HIGH ELECTROLYTE AGRICULTURAL FORMULATIONS | AQP1, HDHD5, AQP3 | ALDH1A1 2800/4885TSHR 3734/4885HTR2A 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.