Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28123863 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTRAB9ASIGMAR1 | |
| SCHEMBL6965526 | 0.77 | CYP19A1 (0.70) | SMN1; SMN2LMNAHTTRAB9AALDH1A1 | |
| SCHEMBL28178599 | 0.74 | RAB9A (0.68) | SMN1; SMN2LMNAHTTRAB9ACYP2A13 | |
| SCHEMBL30364150 | 0.74 | GAA (0.50) | SMN1; SMN2LMNAHTTRAB9ASIGMAR1 | |
| SCHEMBL2202098 | 0.74 | GAA (0.50) | SMN1; SMN2LMNAHTTRAB9ASIGMAR1 | |
| SCHEMBL28003319 | 0.74 | POLB (0.69) | SMN1; SMN2LMNASIGMAR1CYP2A13MAP3K14 | |
| SCHEMBL10500678 | 0.73 | ALDH1A1 (0.52) | LMNACYP2A13IDO1KDM4EALDH1A1 | |
| SCHEMBL11482473 | 0.73 | KDM4E (0.41) | SMN1; SMN2LMNAHTTRAB9ASIGMAR1 | |
| SCHEMBL11360607 | 0.73 | SIGMAR1 (0.85) | SMN1; SMN2LMNAHTTRAB9ASIGMAR1 | |
| SCHEMBL27383724 | 0.73 | CYP11B1 (0.61) | SMN1; SMN2LMNAHTTRAB9ACYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-A | Sophoridine pyrroles, indole derivatives and the preparation method and application thereof | 广西大学 | 2018-08-03 | — | — | CN | claimed |
| US-20220193041-A1 | NOVEL COMPOUND AND METHOD FOR PREVENTING OR TREATING OF RESPIRATORY DISEASES COMPRISING THE SAME AS AN ACTIVE INGREDIENT | Yonsei University, University - Industry Foundation (UIF) (KR) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193041-A1 | NOVEL COMPOUND AND METHOD FOR PREVENTING OR TREATING OF RESPIRATORY DISEASES COMPRISING THE SAME AS AN ACTIVE INGREDIENT | EPX, CFTR, MPO | SMN1; SMN2 1363/4885LMNA 393/4885HTT 2494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.