Propanocaine

Propanocaine

SCHEMBL24545

CCN(CC)CC[C@H](OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ UTS2R Q9UKP6 7/20 0.54
▸ LMNA P02545 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ ALDH1A1 P00352 2/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ SLC6A9 P48067 1/20 0.48
▸ CHRM2 P08172 1/20 0.47
▸ CHRM4 P08173 1/20 0.47
▸ CHRM1 P11229 1/20 0.47
▸ CHRM3 P20309 1/20 0.47
▸ SIGMAR1 Q99720 1/20 0.46
▸ MAPT P10636 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propanocaine SCHEMBL24544 1.00 UTS2R (0.54) UTS2RLMNACYP1A2CYP2D6ALDH1A1
Propanocaine SCHEMBL4180296 0.99 UTS2R (0.53) UTS2RLMNACYP1A2CYP2D6ALDH1A1
Propanocaine SCHEMBL4180298 0.99 UTS2R (0.53) UTS2RLMNACYP1A2CYP2D6ALDH1A1
Elucaine SCHEMBL635291 0.85 ALDH1A1 (0.46) UTS2RLMNACYP1A2CYP2D6ALDH1A1
SCHEMBL27399397 0.83 UTS2R (0.50) UTS2RLMNAALDH1A1CYP3A4MAPT
SCHEMBL1785848 0.80 TSHR (0.52) UTS2RLMNAALDH1A1SIGMAR1MAPT
SCHEMBL3817682 0.80 TSHR (0.52) UTS2RLMNAALDH1A1CYP3A4SMN1; SMN2
SCHEMBL2455385 0.79 ALDH1A1 (0.48) UTS2RLMNAALDH1A1SMN1; SMN2SIGMAR1
SCHEMBL9341086 0.78 ALDH1A1 (0.50) UTS2RLMNAALDH1A1SMN1; SMN2SIGMAR1
SCHEMBL28637211 0.78 UTS2R (0.51) UTS2RLMNACYP1A2ALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1894 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT UNIV KOREA RES & BUS FOUND (KR) 2026-04-30 — — US claimed
EP-4436552-B1 GASTRO-RETENTIVE ORAL DOSAGE UNIT CONTAINING A LOCAL ANAESTHETIC OREXA B V (NL) 2026-02-04 — — EP claimed
WO-2025235864-A1 COATED NEEDLE ADMINISTRATION SYSTEMS EVOLUS, INC. (US) 2025-11-13 — — WO claimed
EP-4578441-A1 TREATMENT OF LOCALIZED PAIN PlantTec Medical GmbH (DE) 2025-07-02 — — EP claimed
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics BIOPOLIMERI S.R.L. (IT) 2025-06-17 — — US claimed
US-20250186364-A1 COMBINATION OF ANTISPASMODIC AND ANESTHETIC AGENTS FOR TOPICAL PRODUCTS AND THEIR METHOD OF USE PRIMA INNOVATIONS, LLC 2025-06-12 — — US claimed
EP-4362994-B1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS BIOPOLIMERI S R L (IT) 2025-03-12 — — EP claimed
WO-2025043048-A1 METHODS AND SYSTEMS FOR DELIVERY OF MODIFIED AGAROSE POLYSACCHARIDES RELIVE THERAPEUTICS INC. (US) 2025-02-27 — — WO claimed
US-20250009689-A1 GASTRO-RETENTIVE ORAL DOSAGE UNIT CONTAINING A LOCAL ANAESTHETIC OREXA B.V. (NL) 2025-01-09 — — US claimed
EP-3703802-B9 NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF CLEXIO BIOSCIENCES LTD (IL) 2024-12-04 — — EP claimed
US-6297290-B2 INTENDED TO ANESTHETIZE THE SKIN OR THE MUCOUS MEMBRANES OR TO TREAT PRURITUS. CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOQUES GALDERMA (C.I.R.D. GALDERMA) (FR) 2001-10-02 — — US claimed
EP-1027015-A4 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE GALIN MILES A (US) 2001-06-27 — — EP claimed
WO-2001043733-A2 COMPOSITIONS, KITS, APPARATUS, AND METHODS FOR INHIBITING CEPHALIC INFLAMMATION LEVIN BRUCE H (US) 2001-06-21 — — WO claimed
US-20010004644-A1 Compositions, kits, apparatus, and methods for inhibiting cephalic inflammation LEVIN BRUCE H (US) 2001-06-21 — — US claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 — — EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO claimed
EP-1027015-A1 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE Galin, Miles A. (US) 2000-08-16 — — EP claimed
US-5972326-A Controlled release of pharmaceuticals in the anterior chamber of the eye IOLTECH (FR) 1999-10-26 — — US claimed
WO-1998041171-A1 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE GALIN MILES A (US) 1998-09-24 — — WO claimed
US-4041174-A INJECTING AN ESTER LOCAL ANESTHETIC ROM-AMER PHARMACEUTICALS, LTD. (US) 1977-08-09 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics CD44, HCAR3, HCAR2 UTS2R 3586/4885LMNA 1981/4885CYP1A2 1332/4885
US-20010004644-A1 Compositions, kits, apparatus, and methods for inhibiting cephalic inflammation CXCR5, CCL5, C5AR2 UTS2R 2610/4885LMNA 1480/4885CYP1A2 1652/4885
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT CES2, DAGLA, ACHE UTS2R 4771/4885LMNA 1300/4885CYP1A2 1231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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