Sugi Predict

Sugi Predict / Compounds / Cholesterol

Cholesterol

Cholesterol

SCHEMBL245456

CC(C)C(=O)O.CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.89

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OSBP P22059 4/20 0.89
▸ RORC P51449 3/20 0.89
▸ OSBP2 Q969R2 2/20 0.89
▸ USP2 O75604 1/20 0.89
▸ LMNA P02545 1/20 0.89
▸ ABCB1 P08183 1/20 0.89
▸ CYP46A1 Q9Y6A2 1/20 0.89
▸ NR1H3 Q13133 7/20 0.77
▸ EPHA2 P29317 1/20 0.77
▸ GRIN1 Q05586 3/20 0.76
▸ GRIN2A Q12879 3/20 0.76
▸ NPC1L1 Q9UHC9 2/20 0.73
▸ CRYAB P02511 1/20 0.73
▸ HMGCR P04035 1/20 0.73
▸ ITGB3 P05106 1/20 0.73
▸ ITGAV P06756 1/20 0.73
▸ SREBF2 Q12772 1/20 0.73
▸ GRIN2B Q13224 2/20 0.72
▸ POLA1 P09884 1/20 0.71
▸ DHCR24 Q15392 2/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cholesterol SCHEMBL27666236 1.00 OSBP (0.89) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL27668883 0.96 OSBP (0.93) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL1369602 0.96 OSBP (0.93) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL29502101 0.96 OSBP (0.93) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL23409665 0.95 OSBP (0.88) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL8899126 0.95 OSBP (0.88) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL8899129 0.95 OSBP (0.88) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL30101141 0.95 OSBP (0.91) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL25657 0.95 OSBP (0.91) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL31090041 0.95 OSBP (0.91) OSBPRORCOSBP2USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060115445-A1 Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents L'OREAL S.A. (FR) 2006-06-01 — — US claimed
EP-1647259-A1 use for treatment of keratinic materials of compositions comprising electrophilic monomers and agents forming liquid crystals L'OREAL (FR) 2006-04-19 — — EP claimed
US-6328910-B1 FOR IN SITU FORMATION OF AN POLYMERIC CYANOACRYLATE FILM ON MAMMALIAN SKIN WHICH CAN BE USED TO MONITOR THE SURFACE SKIN TEMPERATURE OF MAMMAL MEDLOGIC GLOBAL CORPORATION 2001-12-11 — — US claimed
US-6315981-B1 USED FOR OBTAINING IMAGE OF AN INTERNAL REGION OF HUMANS IMARX THERAPEUTICS, INC. 2001-11-13 — — US claimed
EP-0760684-A4 GAS FILLED MICROSPHERES AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX PHARMACEUTICAL CORP (US) 2000-03-15 — — EP claimed
EP-0740528-A4 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP (US) 1998-04-01 — — EP claimed
US-5733572-A Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles IMARX PHARMACEUTICAL CORP. (US) 1998-03-31 — — US claimed
JP-H10500692-A — — 1998-01-20 — — JP claimed
EP-0797433-A4 GAS FILLED MICROSPHERES AS MAGNETIC RESONANCE IMAGING CONTRAST AGENTS IMARX PHARMACEUTICAL CORP (US) 1997-12-03 — — EP claimed
EP-0797433-A1 GAS FILLED MICROSPHERES AS MAGNETIC RESONANCE IMAGING CONTRAST AGENTS ImaRx Pharmaceutical Corp. (US) 1997-10-01 — — EP claimed
CN-1160357-A Gas filled microspheres as computed tomography contrast agents IMARX PHARMACEUTICAL CORP (US) 1997-09-24 — — CN claimed
EP-0760684-A1 GAS FILLED MICROSPHERES AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX PHARMACEUTICAL CORP. (US) 1997-03-12 — — EP claimed
EP-0740528-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1996-11-06 — — EP claimed
WO-1995032006-A1 GAS FILLED MICROSPHERES AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX, PHARMACEUTICAL CORP. (US) 1995-11-30 — — WO claimed
WO-1995024184-A1 GAS FILLED MICROSPHERES AS MAGNETIC RESONANCE IMAGING CONTRAST AGENTS UNGER EVAN C (US) 1995-09-14 — — WO claimed
WO-1995015118-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1995-06-08 — — WO claimed
US-12427208-B2 Iodinated phenolic lipids and methods and cosolvent systems for iodination of phenolic lipids UNIVERSITY OF CINCINNATI (US) 2025-09-30 — — US disclosed
US-20250295806-A1 IMMUNOSTIMULATORY NANOPARTICLE UNIV CASE WESTERN RESERVE (US) 2025-09-25 — — US disclosed
WO-1995032006-A1 GAS FILLED MICROSPHERES AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX, PHARMACEUTICAL CORP. (US) 1995-11-30 — — WO disclosed
WO-1995032005-A1 STABILIZED HOMOGENOUS SUSPENSIONS AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX PHARMACEUTICAL CORP. (US) 1995-11-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060115445-A1 Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents KRT18, PRKDC, CUTA OSBP 2396/4885RORC 3212/4885OSBP2 2545/4885
US-12427208-B2 Iodinated phenolic lipids and methods and cosolvent systems for iodination of phenolic lipids FABP4, LCAT, HDLBP OSBP 20/4885RORC 961/4885OSBP2 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.