SCHEMBL2455407

SCHEMBL2455407

COc1ccc(C=Nc2ccc(N=Cc3ccc(OC)cc3)c3ccccc23)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
GAA P10253 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
S100B P04271 1/20 0.51
CYP1B1 Q16678 1/20 0.49
TRPA1 O75762 1/20 0.48
RRM1 P23921 1/20 0.48
G6PC1 P35575 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NPC1 O15118 1/20 0.46
TP53 P04637 1/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PTGS2 P35354 2/20 0.45
PTGS1 P23219 1/20 0.45
CA12 O43570 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2452233 0.88 ALDH1A1 (0.52) ALDH1A1GAAL3MBTL1S100BCYP1B1
SCHEMBL9947515 0.84 RRM1 (0.54) ALDH1A1GAAL3MBTL1S100BCYP1B1
SCHEMBL3272348 0.81 GAA (0.57) ALDH1A1GAAL3MBTL1S100BCYP1B1
SCHEMBL11135305 0.81 ALDH1A1 (0.46) ALDH1A1GAAL3MBTL1S100BMEN1
SCHEMBL29376660 0.79 S100B (0.57) ALDH1A1GAAL3MBTL1S100BTRPA1
SCHEMBL2544403 0.78 LMNA (0.50) ALDH1A1GAAL3MBTL1RRM1MEN1
SCHEMBL2544406 0.78 LMNA (0.50) ALDH1A1GAAL3MBTL1RRM1MEN1
SCHEMBL443413 0.78 S100B (0.69) ALDH1A1GAAL3MBTL1S100BTRPA1
SCHEMBL443412 0.78 S100B (0.69) ALDH1A1GAAL3MBTL1S100BTRPA1
SCHEMBL2454117 0.77 GAA (0.54) ALDH1A1GAAL3MBTL1S100BTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
US-20170336663-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2017-11-23 US disclosed
EP-3215587-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF Gauzy Ltd. (IL) 2017-09-13 EP disclosed
EP-3209748-A1 METAL ORGANIC LIQUID CRYSTAL DYES Gauzy Ltd (IL) 2017-08-30 EP disclosed
WO-2016071908-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2016-05-12 WO disclosed
US-20150009456-A1 Polymer-stabilized thermotropic liquid crystal device ROSELLA HOLDINGS LIMITED (GG) 2015-01-08 US disclosed
EP-0656927-B1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S C P A (IT) 1999-12-01 EP disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 EP disclosed
US-5843333-A Metallo organo liquid crystals in a polymer matrix SNIARICERCHE S.C.P.A (IT) 1998-12-01 US disclosed
EP-0803525-A2 Chiral anisotropic thermosets (cat) in polymer stabilized liquid crystals Sniaricerche S.C.P.A. (IT) 1997-10-29 EP disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 EP disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed
EP-0656927-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX Sniaricerche S.C.P.A. (IT) 1995-06-14 EP disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 WO disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed