Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Tetrahydrofuran. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL3181441 | 0.96 | ALDH1A1 (0.73) | — | |
| Tetrahydrofuran SCHEMBL49157 | 0.96 | — | — | |
| Tetrahydrofuran SCHEMBL5244965 | 0.96 | ALDH1A1 (0.73) | — | |
| Tetrahydrofuran SCHEMBL1708038 | 0.96 | ALDH1A1 (0.73) | — | |
| Tetrahydrofuran SCHEMBL18167417 | 0.96 | ALDH1A1 (0.73) | — | |
| Tetrahydrofuran SCHEMBL3595372 | 0.93 | ALDH1A1 (0.57) | — | |
| Methyl Alcohol SCHEMBL9304289 | 0.92 | — | — | |
| Tetrahydrofuran SCHEMBL1615823 | 0.92 | — | — | |
| Methyl Alcohol SCHEMBL1534171 | 0.92 | ALDH1A1 (0.67) | — | |
| Tetrahydrofuran SCHEMBL11075183 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 865 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510567-A | Method for preparing high-purity alfaxalone | 长沙启晟合研医药科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-115677668-B | Anserine derivative, and preparation method and application thereof | 东南大学 | 2023-12-05 | — | — | CN | claimed |
| CN-115677668-A | Anserine derivative and preparation method and application thereof | 东南大学 | 2023-02-03 | — | — | CN | claimed |
| CN-111721874-B | HPLC method for separating tadalafil and chiral isomer thereof | 杭州颐源医药技术有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-113861145-A | Guaianolide compound and preparation method and application thereof | 湖北第二师范学院 | 2021-12-31 | — | — | CN | claimed |
| CN-109928966-B | Metal organic framework material based on phenothiazine and preparation method and application thereof | 山东师范大学 | 2021-04-02 | — | — | CN | claimed |
| CN-111721874-A | HPLC method for separating tadalafil and chiral isomer thereof | 南京赛尔健生物技术有限公司 | 2020-09-29 | — | — | CN | claimed |
| CN-111721873-A | Method for separating dihydromyricetin and (2S,3S) chiral isomer thereof based on reversed-phase HPLC | 南京赛尔健生物技术有限公司 | 2020-09-29 | — | — | CN | claimed |
| CN-109928966-A | Metal-organic framework material and its preparation method and application based on phenthazine | 山东师范大学 | 2019-06-25 | — | — | CN | claimed |
| CN-104914174-B | A kind of content assaying method of injection ginkgo diterpenoid-lactone | 江苏康缘药业股份有限公司 | 2017-07-25 | — | — | CN | claimed |
| CN-1814127-A | Shenbao preparation, its preparing method and quality control method | MAO XIAOMIN (CN) | 2006-08-09 | — | — | CN | claimed |
| CN-1800845-A | Quality control method for gingko lactone lyophilized powder for injection | JIANGSU KANION PHARMACEUTICAL (CN) | 2006-07-12 | — | — | CN | claimed |
| CN-1241610-C | Medicinal composition for preventing and curing prostatitis and hyperplasia of prostate and its preparing method | CHINESE MEDICINE SCIENCE AND T (CN) | 2006-02-15 | — | — | CN | claimed |
| CN-1714641-A | Preparation and application of insecticidal active substance in stellera chamaejasme | UNIV SICHUAN (CN) | 2006-01-04 | — | — | CN | claimed |
| US-20040259814-A1 | Synthesis of solanum glycosides | GLYCOMED SCIENCES LIMITED (KY) | 2004-12-23 | — | — | US | claimed |
| CN-1520814-A | Ginkgo leaf extract and its preparation | 江苏康缘药业股份有限公司 | 2004-08-18 | — | — | CN | claimed |
| CN-1511573-A | Medicinal composition for preventing and curing prostatitis and hyperplasia of prostate and its preparing method | 中国中医药科技开发交流中心 | 2004-07-14 | — | — | CN | claimed |
| US-20020119390-A1 | Positive photoresist composition and process for forming resist pattern using same | TOKYO OHKA KOGYO CO., LTD. | 2002-08-29 | — | — | US | claimed |
| US-6379859-B2 | MIXTURE OF ALKALI SOLUBLE POLYMER AND PHOTOSENSITIZERS | TOKYO OHKA KOGYO CO., LTD. (JP) | 2002-04-30 | — | — | US | claimed |
| US-20020012865-A1 | POSITIVE PHOTORESIST COMPOSITION AND PROCESS FOR FORMING RESIST PATTERN USING SAME | TOKYO OHKA KOGYO CO., LTD. (JP) | 2002-01-31 | — | — | US | claimed |