Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645103 | 0.77 | METAP2 (0.50) | MEN1KMT2ARPA1METAP2NOTUM | |
| Methylamine SCHEMBL27885520 | 0.75 | METAP2 (0.46) | IKBKBMAP3K14MEN1KMT2ARPA1 | |
| Hydrochloric Acid SCHEMBL10565482 | 0.75 | METAP2 (0.48) | MEN1KMT2ARPA1METAP2NOTUM | |
| SCHEMBL4764742 | 0.73 | POLB (0.53) | MAPTNPSR1MAPK1KDM4ETDP1 | |
| SCHEMBL2456914 | 0.72 | AKT1 (0.51) | MEN1KMT2A | |
| SCHEMBL2455752 | 0.71 | MEN1 (0.44) | IKBKBMAP3K14MEN1KMT2AMAPT | |
| SCHEMBL28822256 | 0.69 | LTA4H (0.51) | MEN1KMT2AMETAP2NOTUMMAPT | |
| SCHEMBL2453925 | 0.68 | MEN1 (0.42) | IKBKBMAP3K14MEN1KMT2AMAPT | |
| SCHEMBL2456950 | 0.68 | MEN1 (0.42) | IKBKBMAP3K14MEN1KMT2AMAPT | |
| SCHEMBL13165378 | 0.68 | APEX1 (0.48) | MEN1KMT2AKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958948-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1958948-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | PLPBP, PNPO, PDXK | IKBKB 2953/4885MAP3K14 1151/4885MEN1 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.