SCHEMBL24575474

SCHEMBL24575474

CCCc1ccc(C(C)N(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
ACACB O00763 2/20 0.41
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
CA2 P00918 1/20 0.38
ACACA Q13085 1/20 0.38
PYCR1 P32322 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MGLL Q99685 1/20 0.36
PLK1 P53350 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18899612 0.83 TSHR (0.48) LPLLIPGALDH1A1MAPTPYCR1
SCHEMBL18762840 0.79 CHRNA7 (0.43) KMT2AALDH1A1MAPTPYCR1KDM4E
SCHEMBL597719 0.78 IDO1 (0.50) LPLLIPGACACBKMT2AALDH1A1
SCHEMBL9621041 0.78 LPL (0.46) LPLLIPGACACBKMT2AALDH1A1
SCHEMBL11141687 0.77 ALOX5 (0.40) KMT2AALDH1A1MAPTPYCR1KDM4E
SCHEMBL2491588 0.75 LPL (0.48) LPLLIPGACACBKMT2ACA2
SCHEMBL7043601 0.74 ADRB2 (0.48) LPLLIPGACACBKMT2AALDH1A1
SCHEMBL14540984 0.74 LPL (0.48) LPLLIPGACACBKMT2ACA2
SCHEMBL20036657 0.74 LPL (0.43) LPLLIPGACACBALDH1A1NPC1
SCHEMBL14396739 0.74 L3MBTL1 (0.43) LPLLIPGACACBKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022133594-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-30 WO disclosed