Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577224 | 0.76 | CYP11B2 (0.36) | CREBBP | |
| SCHEMBL24577371 | 0.75 | COMT (0.39) | — | |
| SCHEMBL24577874 | 0.71 | FLT3 (0.38) | CREBBP | |
| SCHEMBL24578878 | 0.68 | KDR (0.38) | — | |
| SCHEMBL24578525 | 0.68 | BRAF (0.30) | — | |
| SCHEMBL24577085 | 0.65 | KIT (0.39) | — | |
| SCHEMBL24577471 | 0.63 | BACE1 (0.40) | — | |
| SCHEMBL12195722 | 0.62 | HTR7 (0.35) | CREBBP | |
| SCHEMBL24578564 | 0.61 | ALDH1A1 (0.42) | CREBBP | |
| SCHEMBL24578796 | 0.60 | MAP4K1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |