Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458059 | 1.00 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10739476 | 0.84 | ALDH1A1 (0.52) | CYP2C9AKR1C3ITGB1ITGA4ALDH1A1 | |
| SCHEMBL10739481 | 0.84 | ALDH1A1 (0.52) | CYP2C9AKR1C3ITGB1ITGA4ALDH1A1 | |
| SCHEMBL388142 | 0.84 | AKR1C3 (0.57) | AKR1C3AKR1C1ALDH1A1HTTMAPT | |
| SCHEMBL388143 | 0.84 | AKR1C3 (0.57) | AKR1C3AKR1C1ALDH1A1HTTMAPT | |
| SCHEMBL786716 | 0.84 | AKR1C3 (0.57) | AKR1C3AKR1C1ALDH1A1HTTMAPT | |
| SCHEMBL27569641 | 0.83 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1520588 | 0.83 | ALDH1A1 (0.44) | CYP2C9AKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL8652648 | 0.83 | ALDH1A1 (0.44) | CYP2C9AKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL1520586 | 0.83 | ALDH1A1 (0.44) | CYP2C9AKR1C3AKR1C2AKR1C1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514739-B1 | Substituted beta-phenyl-alpha-hydroxy propanoic acid, synthesis method and use thereof | UNIV NORTHWEST (CN) | 2016-12-21 | — | — | EP | disclosed |
| EP-2514739-A1 | Substituted beta-phenyl-alpha-hydroxy propanoic acid, synthesis method and use thereof | Northwest University (CN) | 2012-10-24 | — | — | EP | disclosed |
| US-8017786-B2 | Substituted β-phenyl-α-hydroxy-propanoic acid, synthesis method and use thereof | NORTHWEST UNIVERSITY (CN) | 2011-09-13 | — | — | US | disclosed |
| US-20090131677-A1 | SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXY-PROPANOIC ACID, SYNTHESIS METHOD AND USE THEREOF | NORTHWEST UNIVERSITY (CN) | 2009-05-21 | — | — | US | disclosed |
| EP-2019090-A1 | SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXY PROPANOIC ACID, SYNTHESIS METHOD AND USE THEREOF | Northwest University (CN) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131677-A1 | SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXY-PROPANOIC ACID, SYNTHESIS METHOD AND USE THEREOF | P4HA1, HAO1, PCCA | HDAC3 1615/4885HDAC4 3268/4885HDAC1 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.