Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388142 | 1.00 | AKR1C3 (0.57) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL388143 | 1.00 | AKR1C3 (0.57) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL387760 | 0.98 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| Methyl Alcohol SCHEMBL8740650 | 0.98 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15085946 | 0.90 | TP53 (0.56) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5498513 | 0.89 | MEN1 (0.46) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL12561790 | 0.89 | RECQL (0.53) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL27415288 | 0.85 | RAB9A (0.50) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10739476 | 0.85 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10739481 | 0.85 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592552-B1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | DU PONT (US) | 1997-05-28 | — | — | EP | claimed |
| US-5559267-A | ENANTIOMORPHS, STEREOCHEMICAL CONTROL AND ASSYMETRIC INDUCTION, HYDROGENATION OF UNSATURATED ESTERS, COORDINATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | claimed |
| EP-0592552-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES. | DU PONT (US) | 1994-04-20 | — | — | EP | claimed |
| WO-1993001199-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-21 | — | — | WO | claimed |
| US-8785655-B2 | Ionic liquid solvents | DUBLIN CITY UNIVERSITY (IE) | 2014-07-22 | — | — | US | disclosed |
| US-20130035225-A1 | ORGANIC/INORGANIC HYBRID CATALYTIC MATERIALS, THEIR PREPARATION, USE IN SELECTIVE PROCESSES AND REACTORS CONTAINING THEM | NIPPON KODOSHI CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
| US-20120071661-A1 | Ionic Liquid Solvents | DUBLIN CITY UNIVERSITY (IE) | 2012-03-22 | — | — | US | disclosed |
| EP-2223915-A1 | Ionic liquid solvents | Dublin City University (IE) | 2010-09-01 | — | — | EP | disclosed |
| US-7763739-B2 | bidentante optionally N-containing P-ligands embracing a two-ring-system; for transition metal complexes to be used as catalysts | Evonik Degussa, GmbH (DE) | 2010-07-27 | — | — | US | disclosed |
| EP-1568701-B1 | TRANSITION METAL COMPLEX HAVING DIPHOSPHINE COMPLEX AS LIGAND | TAKEDA PHARMACEUTICAL (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-7547694-B2 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-16 | — | — | US | disclosed |
| US-20080306264-A1 | bidentante optionally N-containing P-ligands embracing a two-ring-system; for transition metal complexes to be used as catalysts | DEGUSSA AG (DE) | 2008-12-11 | — | — | US | disclosed |
| EP-0408340-A2 | Ruthenium-optically active phoshine complex useful as catalyst | Takasago International Corporation (JP) | 1991-01-16 | — | — | EP | disclosed |
| US-4654176-A | Sulphonated chiral phosphines, their preparation and their use | RHONE-POULENC SANTE (FR) | 1987-03-31 | — | — | US | disclosed |
| US-4464306-A | HYDROGENATION CATALYSTS, RHODIUM COMPOUNDS | MONSANTO COMPANY (US) | 1984-08-07 | — | — | US | disclosed |
| US-4376870-A | USED AS HYDROGENATION CATALYSTS FOR OLEFINS | MONSANTO COMPANY (US) | 1983-03-15 | — | — | US | disclosed |
| US-4306082-A | Optically active tertiary phosphine oxides and tertiary phosphines and processes for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1981-12-15 | — | — | US | disclosed |
| US-4010181-A | BIS(PHOSPHINOMETHYL)CYCLOBUTANE RHODIUM COMPLEXES | RHONE-POULENC S.A. (FR) | 1977-03-01 | — | — | US | disclosed |
| US-3978101-A | HYDROGENATION CATALYSTS | RHONE-POULENC S.A. (FR) | 1976-08-31 | — | — | US | disclosed |
| US-3949000-A | COMPLEX FORMERS | RHONE-POULENC S.A. (FR) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306264-A1 | bidentante optionally N-containing P-ligands embracing a two-ring-system; for transition metal complexes to be used as catalysts | CCNE2, NDUFS2, SOD1 | AKR1C3 2047/4885ALDH1A1 1571/4885TSHR 4313/4885 |
| US-20120071661-A1 | Ionic Liquid Solvents | EBP, PAICS, HACD3 | AKR1C3 625/4885ALDH1A1 834/4885TSHR 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.