Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786716 | 1.00 | AKR1C3 (0.57) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL388143 | 1.00 | AKR1C3 (0.57) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL387760 | 0.98 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| Methyl Alcohol SCHEMBL8740650 | 0.98 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15085946 | 0.90 | TP53 (0.56) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5498513 | 0.89 | MEN1 (0.46) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL12561790 | 0.89 | RECQL (0.53) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL27415288 | 0.85 | RAB9A (0.50) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10739476 | 0.85 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10739481 | 0.85 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114667823-B | Method for accelerating germination of tomato seeds by using magnetic field | 安徽省富美四季农业科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-115785067-A | Preparation method of impurity compound of esomeprazole thioether | 北京京卫燕康药物研究所有限公司 | 2023-03-14 | — | — | CN | claimed |
| WO-2018204829-A1 | METHODS FOR PREVENTING NEURAL TUBE DEFECTS IN DIABETIC PREGNANCY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-11-08 | — | — | WO | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | claimed |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) | 2012-04-12 | — | — | US | claimed |
| EP-1747059-A1 | PERVAPORATION COMPOSITE MEMBRANES | McMaster University (CA) | 2007-01-31 | — | — | EP | claimed |
| US-20060000778-A1 | high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers | MCMASTER UNIVERSITY (CA) | 2006-01-05 | — | — | US | claimed |
| WO-2005102503-A1 | PERVAPORATION COMPOSITE MEMBRANES | MCMASTER UNIVERSITY (CA) | 2005-11-03 | — | — | WO | claimed |
| EP-0739333-A1 | SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-30 | — | — | EP | claimed |
| US-5559267-A | ENANTIOMORPHS, STEREOCHEMICAL CONTROL AND ASSYMETRIC INDUCTION, HYDROGENATION OF UNSATURATED ESTERS, COORDINATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | claimed |
| US-5510507-A | COORDINATION CATALYSTS; EFFICIENT ENANTIOSELECTIVITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-23 | — | — | US | claimed |
| WO-1995018787-A1 | SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-07-13 | — | — | WO | claimed |
| EP-0592552-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES. | DU PONT (US) | 1994-04-20 | — | — | EP | claimed |
| WO-1993001199-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-21 | — | — | WO | claimed |
| EP-0252216-B1 | MICROBIOLOGICALLY PRODUCED ALPHA-ACETYLAMINO CINNAMIC ACID ACYLASE, METHOD OF ITS PRODUCTION AND ITS USE | Degussa Aktiengesellschaft (DE) | 1992-01-29 | — | — | EP | claimed |
| US-4795816-A | 2-methyl-4-benzyl-5-oxazolidinone | THE DOW CHEMICAL COMPANY (US) | 1989-01-03 | — | — | US | claimed |
| EP-0077099-A2 | Process for preparing amino acids and their esters | ANIC S.p.A. (IT) | 1983-04-20 | — | — | EP | claimed |
| US-4328364-A | RHODIUM CATALYST | SNAMPROGETTI, S.P.A. (IT) | 1982-05-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | AKR1C3 4367/4885ALDH1A1 3087/4885TSHR 1605/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | AKR1C3 4367/4885ALDH1A1 3087/4885TSHR 1605/4885 |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | AKR1C3 4367/4885ALDH1A1 3087/4885TSHR 1605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.