SCHEMBL24596644

SCHEMBL24596644

c1ccc(-c2ccc(-c3nc4c(ccc5ccccc54)nc3-n3c4cccc5c4c4c6c(cccc6ccc43)-c3ccccc3-5)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.32
PRMT3 O60678 1/20 0.32
CARM1 Q86X55 1/20 0.32
EHMT2 Q96KQ7 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
PRMT1 Q99873 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
RECQL P46063 1/20 0.32
MMP14 P50281 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
DHODH Q02127 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23332450 0.98 PRMT5 (0.33) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL24596578 0.96 PRMT5 (0.32) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL24245538 0.96 PRMT5 (0.33) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL24596623 0.95 PRMT5 (0.34) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL23332449 0.94 PRMT5 (0.33) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL24245589 0.93 PRMT5 (0.34) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL24116996 0.93 FLT3 (0.32) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL22824978 0.92 PRMT5 (0.35) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL24245537 0.92 ALDH1A1 (0.31) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL24245535 0.91 PRMT5 (0.33) PRMT5PRMT3CARM1EHMT2PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220399506-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-15 US disclosed
US-20220393116-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed
US-20220216433-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216433-A1 ELECTROLUMINESCENT DEVICE EML4, EMC2, L1CAM PRMT5 1576/4885PRMT3 2374/4885CARM1 1313/4885
US-20220393116-A1 ELECTROLUMINESCENT DEVICE L1CAM, MCOLN2, MCOLN1 PRMT5 2837/4885PRMT3 3757/4885CARM1 2968/4885
US-20220399506-A1 ELECTROLUMINESCENT DEVICE L1CAM, LDHA, LDHB PRMT5 4116/4885PRMT3 4563/4885CARM1 4130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.