Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614806 | 0.95 | CA1 (0.38) | GPR84L3MBTL1TDP1ALOX5MAOA | |
| SCHEMBL24614839 | 0.92 | GPR84 (0.34) | GPR84L3MBTL1TDP1ALOX5MAOA | |
| SCHEMBL24614840 | 0.92 | MAOA (0.39) | GPR84L3MBTL1TDP1ALOX5MAOA | |
| SCHEMBL24614638 | 0.92 | TDP1 (0.38) | GPR84L3MBTL1TDP1ALOX5MAOA | |
| SCHEMBL18266973 | 0.91 | L3MBTL1 (0.42) | GPR84L3MBTL1TDP1ALOX5MAOA | |
| SCHEMBL17944463 | 0.91 | L3MBTL1 (0.39) | GPR84L3MBTL1TDP1ALOX5MAOA | |
| SCHEMBL24614911 | 0.90 | ALOX5 (0.39) | GPR84L3MBTL1TDP1ALOX5MAOB | |
| SCHEMBL24614810 | 0.89 | ALOX5 (0.36) | GPR84L3MBTL1TDP1ALOX5MAOA | |
| SCHEMBL24614800 | 0.88 | ALOX5 (0.38) | GPR84L3MBTL1TDP1ALOX5MAOA | |
| SCHEMBL24614799 | 0.88 | L3MBTL1 (0.39) | L3MBTL1TDP1ALOX5MAOBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | GPR84 3746/4885L3MBTL1 2463/4885TDP1 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.