Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21128963 | 0.80 | ACHE (0.47) | TRPM8AOC3ACP3SLC6A2SLC6A4 | |
| SCHEMBL4310309 | 0.77 | ALDH1A1 (0.47) | TRPM8AOC3ALDH1A1MAPT | |
| SCHEMBL31061559 | 0.77 | ALDH1A1 (0.47) | TRPM8AOC3ALDH1A1MAPT | |
| SCHEMBL9626322 | 0.75 | ALOX5 (0.55) | — | |
| SCHEMBL7510418 | 0.74 | ACP3 (0.43) | TRPM8AOC3POLBACP3ALDH1A1 | |
| SCHEMBL5539727 | 0.74 | AOC3 (0.43) | AOC3POLBACP3SLC6A4HPGD | |
| Dimethylformamide SCHEMBL28224251 | 0.73 | POLB (0.55) | AOC3POLBALDH1A1GAAMAPT | |
| SCHEMBL1047528 | 0.71 | ACP3 (0.47) | TRPM8AOC3ACP3ALDH1A1HPGD | |
| SCHEMBL254476 | 0.71 | PGR (0.47) | AOC3ACP3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL2601111 | 0.71 | PNMT (0.47) | AOC3ACP3SLC6A2SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150381-A1 | SELECTIVE INHIBITORS OF ROCK1 AND ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. (US) | 2022-07-14 | — | — | WO | disclosed |