Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619179 | 0.83 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1KHKABCG2 | |
| SCHEMBL24619233 | 0.74 | LPL (0.33) | CYP11B1CYP11B2ESR2 | |
| SCHEMBL29727181 | 0.74 | LPL (0.33) | CYP11B1CYP11B2ESR2 | |
| SCHEMBL9724329 | 0.73 | LMNA (0.50) | MAPTHTTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29727194 | 0.72 | CYP11B2 (0.36) | CYP11B1CYP11B2ALDH1A1KHKESR1 | |
| SCHEMBL24482816 | 0.70 | GPR139 (0.33) | HTTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6766208 | 0.70 | LMNA (0.56) | MAPTHTTALDH1A1KDM4EESR1 | |
| SCHEMBL14525474 | 0.68 | TRPV4 (0.41) | CYP11B1CYP11B2MAPTALDH1A1KHK | |
| SCHEMBL24619651 | 0.68 | KDM4E (0.44) | MAPTALDH1A1DHODHKDM4EHSD17B10 | |
| SCHEMBL24619650 | 0.68 | GPR139 (0.34) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |