SCHEMBL5364899

SCHEMBL5364899

Bc1cc(C)c(F)cc1F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
ACHE P22303 1/20 0.32
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18929647 0.86 ACHE (0.33) ACHE
SCHEMBL12706378 0.83 GPR3 (0.32) GPR3ACHEDAO
Tromethamine SCHEMBL7097633 0.80 MEN1 (0.36)
SCHEMBL10147311 0.78 ACHE (0.40) GPR3ACHEDAO
SCHEMBL10290142 0.77 CYP3A4 (0.42) ACHE
SCHEMBL823783 0.76 ACHE (0.38) GPR3ACHEDAO
SCHEMBL15746143 0.76 GPR84 (0.31)
SCHEMBL12461283 0.75
SCHEMBL261036 0.75 ACHE (0.42) GPR3ACHEDAO
SCHEMBL13264033 0.74 ALDH1A1 (0.37) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217676-B2 Hydrophobization and silica for supported catalyst EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-05-15 US disclosed
EP-1704171-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST ExxonMobil Chemical Patents Inc. (US) 2006-09-27 EP disclosed
WO-2005075526-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO disclosed
US-20050159299-A1 Hydrophobization and silica for supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed