Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | NPY2R | P49146 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523154 | 0.86 | MGLL (0.56) | GAARAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL2867370 | 0.74 | GPR119 (0.53) | MAPTSMN1; SMN2KMT2AUSP2ALDH1A1 | |
| SCHEMBL27906266 | 0.74 | TSHR (0.57) | GAARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11882343 | 0.73 | MGLL (0.72) | GAARAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL952359 | 0.71 | GAA (0.60) | GAARAB9ANPC1MAPTHTT | |
| SCHEMBL13152706 | 0.71 | GAA (0.68) | GAARAB9ANPC1MGLLNPY2R | |
| SCHEMBL24856088 | 0.70 | GAA (0.46) | GAARAB9ANPC1MAPTHTT | |
| SCHEMBL10666406 | 0.70 | GAA (0.63) | GAARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL20324400 | 0.70 | LMNA (0.42) | GAARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL8747418 | 0.69 | RAB9A (0.69) | GAARAB9ANPC1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554554-B1 | EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY | SAREPTA THERAPEUTICS INC (US) | 2022-09-07 | — | — | EP | disclosed |