SCHEMBL2464561

SCHEMBL2464561

CCCCc1ccc([Si](OC)(OC)OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.46
CA1 P00915 1/20 0.46
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
TP53 P04637 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
SHBG P04278 1/20 0.42
CYP3A4 P08684 1/20 0.42
HSPD1 P10809 1/20 0.42
ADRB3 P13945 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5485012 0.94 ALDH1A1 (0.50) CA2ALDH1A1HSD17B10HPGDSMN1; SMN2
SCHEMBL5490593 0.92 HSD17B10 (0.53) ALDH1A1HSD17B10HPGDSMN1; SMN2ESR1
SCHEMBL14267367 0.92 HSD17B10 (0.53) ALDH1A1HSD17B10HPGDSMN1; SMN2ESR1
SCHEMBL31362014 0.89 CA2 (0.41) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL5488548 0.88 LPL (0.42) CA2ALDH1A1PLK1LPLLIPG
SCHEMBL2945374 0.82 CALM1 (0.35) THRATHRB
SCHEMBL17684937 0.82 CA2 (0.44) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL2953186 0.82 CALM1 (0.35) THRATHRB
SCHEMBL17529734 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGD
SCHEMBL2954273 0.79 TAAR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN claimed
CN-112142660-A Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2020-12-29 CN claimed
CN-110095941-B Photosensitive resin composition and method for producing semiconductor element 东丽株式会社 2023-02-17 CN disclosed
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN disclosed
CN-112142660-A Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2020-12-29 CN disclosed
EP-2364844-B1 POLYCARBONATE RESIN LAMINATES SHINETSU CHEMICAL CO (JP) 2020-12-09 EP disclosed
EP-3009480-B1 SILICA-CONTAINING RESIN COMPOSITION AND METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE PRODUCED FROM SILICA-CONTAINING RESIN COMPOSITION NISSAN CHEMICAL CORP (JP) 2019-05-01 EP disclosed
CN-105308123-B The molded product of resin combination and its manufacturing method containing silica and the resin combination containing silica 日产化学工业株式会社 2019-03-29 CN disclosed
EP-2697295-B1 ORGANIC RESIN LAMINATE EXATEC LLC (US) 2018-12-19 EP disclosed
US-9777141-B2 Silica-containing resin composition and method for producing same, and molded article produced from silica-containing resin composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-10-03 US disclosed
US-20160130425-A1 SILICA-CONTAINING RESIN COMPOSITION AND METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE PRODUCED FROM SILICA-CONTAINING RESIN COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-12 US disclosed
US-20120263933-A1 ORGANIC RESIN LAMINATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-18 US disclosed
WO-2012141708-A1 ORGANIC RESIN LAMINATE EXATEC LLC (US) 2012-10-18 WO disclosed
EP-2226352-B1 UV-shielding silicone coating composition and coated article SHINETSU CHEMICAL CO (JP) 2012-07-11 EP disclosed
US-20110223414-A1 POLYCARBONATE RESIN LAMINATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-09-15 US disclosed
EP-2364844-A2 Polycarbonate resin laminates Shin-Etsu Chemical Co., Ltd. (JP) 2011-09-14 EP disclosed
US-20100261022-A1 UV-SHIELDING COATING COMPOSITION AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-10-14 US disclosed
EP-2239308-A1 UV-shielding coating composition and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2010-10-13 EP disclosed
EP-2226352-A2 UV-shielding silicone coating composition and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2010-09-08 EP disclosed
US-20100221557-A1 UV-SHIELDING SILICONE COATING COMPOSITION AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-09-02 US disclosed