Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | EPHB3 | P54753 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24339334 | 0.76 | DRD2 (0.46) | SMN1; SMN2ALDH1A1MAPTP2RX7EPHB3 | |
| SCHEMBL21819232 | 0.76 | LMNA (0.46) | SMN1; SMN2ALDH1A1EPHB3KDM4ELMNA | |
| SCHEMBL661699 | 0.71 | TAAR1 (0.51) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL30874634 | 0.71 | TAAR1 (0.51) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL27592315 | 0.70 | TAAR1 (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL21818673 | 0.69 | POLB (0.42) | SMN1; SMN2ALDH1A1MAPTEPHB3KDM4E | |
| SCHEMBL30301470 | 0.69 | MAPK14 (0.37) | EPHB3 | |
| SCHEMBL30431086 | 0.69 | DRD2 (0.46) | SMN1; SMN2ALDH1A1MAPTEPHB3KDM4E | |
| SCHEMBL506923 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1P2RX7KDM4ELMNA | |
| SCHEMBL1554320 | 0.68 | KDM4E (0.53) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | SMN1; SMN2 3418/4885ALDH1A1 312/4885MAPT 2516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.