SCHEMBL246596

SCHEMBL246596

C=C(C)C(=O)OCCC(F)(F)C(F)(F)S(=O)(=O)OS(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 4/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
HSD11B1 P28845 1/20 0.33
RORC P51449 1/20 0.33
ABCC9 O60706 1/20 0.32
ABCC8 Q09428 1/20 0.32
KCNJ11 Q14654 1/20 0.32
KCNJ8 Q15842 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
THRB P10828 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14321769 0.91 LMNA (0.35) HTTPOLBAPEX1TDP1TSHR
SCHEMBL4268824 0.83 HSD11B1 (0.37) HTTPOLBTSHRKMT2AMEN1
SCHEMBL1656675 0.82 TDP1 (0.44) POLBTDP1KMT2ACYP1A2CYP3A4
SCHEMBL246811 0.81 KMT2A (0.36) HTTPOLBAPEX1TDP1TSHR
SCHEMBL1771449 0.80 RORC (0.35) HTTTDP1TSHRKMT2AMEN1
SCHEMBL1656350 0.77 HSD11B1 (0.38) TSHRKMT2AMEN1HSD11B1RORC
SCHEMBL246595 0.77 HTT (0.35) HTTPOLBAPEX1TDP1TSHR
SCHEMBL14245570 0.76 LMNA (0.37) HTTPOLBAPEX1TDP1TSHR
SCHEMBL2887917 0.75 ALDH1A1 (0.45) POLBTSHRKMT2ACYP1A2CYP3A4
SCHEMBL1533291 0.75 HSD11B1 (0.36) POLBTSHRKMT2AMEN1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9024058-B2 Ammonium fluoroalkanesulfonates and a synthesis method therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2015-05-05 US disclosed
US-20120004447-A1 Ammonium Fluoroalkanesulfonates and a Synthesis Method Therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004447-A1 Ammonium Fluoroalkanesulfonates and a Synthesis Method Therefor NOTUM, FAR1, PFAS HTT 1763/4885POLB 870/4885APEX1 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.