SCHEMBL24671054

SCHEMBL24671054

CC(C)(C)OC(=O)NCCSc1ccc(N)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.49
MTNR1A P48039 2/20 0.47
MTNR1B P49286 2/20 0.47
CA12 O43570 5/20 0.46
CA1 P00915 5/20 0.46
CA2 P00918 5/20 0.46
CA9 Q16790 5/20 0.46
ALDH1A1 P00352 3/20 0.45
MAPK1 P28482 1/20 0.45
SDCBP O00560 1/20 0.43
SDC2 P34741 1/20 0.43
MALT1 Q9UDY8 1/20 0.42
TEAD1 P28347 1/20 0.42
YAP1 P46937 1/20 0.42
TEAD4 Q15561 1/20 0.42
TEAD2 Q15562 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7894530 0.87 MTNR1A (0.48) IDO1MTNR1AMTNR1BCA12CA1
SCHEMBL18295921 0.86 L3MBTL1 (0.55) IDO1MTNR1AMTNR1BALDH1A1MAPK1
SCHEMBL22015112 0.86 ALDH1A1 (0.53) IDO1MTNR1AMTNR1BCA12CA1
SCHEMBL7528860 0.85 MTNR1A (0.62) IDO1MTNR1AMTNR1BALDH1A1MALT1
SCHEMBL13306470 0.85 IDO1 (0.46) IDO1MTNR1AMTNR1BCA12CA1
SCHEMBL3716262 0.84 IDO1 (0.47) IDO1MTNR1AMTNR1BCA12CA1
SCHEMBL21013091 0.84 SDCBP (0.47) IDO1MTNR1AMTNR1BCA12CA1
SCHEMBL20837980 0.83 KMT2A (0.47) IDO1MTNR1AMTNR1BCA12CA1
SCHEMBL445683 0.83 ALDH1A1 (0.48) IDO1MTNR1AMTNR1BCA12CA1
SCHEMBL10493769 0.83 IDO1 (0.46) IDO1MTNR1AMTNR1BCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed