Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.41 |
| ▸ | PGK2 | P07205 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24672262 | 0.87 | POLB (0.38) | HDAC1HDAC4KCNH2APOBEC3ARECQL | |
| SCHEMBL24672263 | 0.81 | LMNA (0.38) | HDAC1HDAC4KCNH2APOBEC3ARECQL | |
| SCHEMBL24673327 | 0.81 | POLB (0.53) | ATMMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24673250 | 0.80 | SIGMAR1 (0.56) | APOBEC3ARECQLAPOBEC3GATMMEN1 | |
| SCHEMBL24672858 | 0.80 | HDAC4 (0.46) | HDAC1HDAC4KCNH2APOBEC3ARECQL | |
| SCHEMBL24673197 | 0.78 | KDM4E (0.45) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL24673258 | 0.75 | MAPT (0.33) | ALDH1A1KDM4E | |
| SCHEMBL24673213 | 0.75 | PGK1 (0.45) | PGK1PGK2HDAC1HDAC4KCNH2 | |
| SCHEMBL24673260 | 0.74 | APOBEC3A (0.51) | APOBEC3ARECQLAPOBEC3GATMMEN1 | |
| SCHEMBL24672258 | 0.73 | KDM4E (0.51) | HDAC1HDAC4APOBEC3ARECQLAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204065-A1 | IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |