Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ATF1 | P18846 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29755073 | 1.00 | GPBAR1 (0.34) | GPBAR1ABL1ATF1NFKB1NR1H2 | |
| SCHEMBL24676945 | 0.78 | RORC (0.38) | GPR119 | |
| SCHEMBL24676012 | 0.77 | GPR119 (0.45) | GPR119 | |
| SCHEMBL24675993 | 0.76 | ALDH1A1 (0.33) | NR1H2NR1H3 | |
| SCHEMBL24676815 | 0.72 | AAK1 (0.35) | GPBAR1ABL1 | |
| SCHEMBL24676469 | 0.72 | AAK1 (0.39) | GPBAR1ABL1ATF1NFKB1PAX8 | |
| SCHEMBL28511505 | 0.71 | ADORA2A (0.37) | PAX8 | |
| SCHEMBL30756386 | 0.69 | AAK1 (0.36) | NR1H2NR1H3GPR119 | |
| SCHEMBL29754868 | 0.69 | PAX8 (0.37) | ABL1PAX8 | |
| SCHEMBL28474596 | 0.66 | USP30 (0.38) | GPR119PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |