SCHEMBL24677423

SCHEMBL24677423

c1ccc(-c2cccc3c2sc2c(-n4c5ccccc5c5cc6c(cc54)c4ccccc4n6-c4ccccc4)cccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
LIMK1 P53667 1/20 0.38
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 3/20 0.35
IL1R1 P14778 1/20 0.35
MEN1 O00255 2/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
ALOX5 P09917 1/20 0.34
MAPK14 Q16539 1/20 0.33
KDR P35968 1/20 0.32
HSD17B10 Q99714 3/20 0.31
MGLL Q99685 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
HTR1A P08908 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24677422 0.95 L3MBTL1 (0.41) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL23072418 0.93 ATM (0.39) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL17640315 0.93 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL10331654 0.93 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL17038455 0.90 KDM4E (0.39) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL24677556 0.89 KDM4E (0.40) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL17228758 0.89 L3MBTL1 (0.43) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL18505103 0.88 L3MBTL1 (0.47) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL17038457 0.88 KDM4E (0.37) L3MBTL1KDM4EATMLIMK1ALDH1A1
SCHEMBL25496651 0.87 ALOX5 (0.36) L3MBTL1KDM4EATMLIMK1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11485706-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485706-B2 Organic electroluminescent materials and devices SOD1, L1CAM, EPCAM L3MBTL1 1135/4885KDM4E 3594/4885ATM 1277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.