Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24682972 | 0.88 | KMT2A (0.34) | MGLLALDH1A1ADRB2KMT2AHSD17B2 | |
| SCHEMBL30701659 | 0.88 | KMT2A (0.34) | MGLLALDH1A1ADRB2KMT2AHSD17B2 | |
| SCHEMBL24682820 | 0.78 | KMT2A (0.35) | ALDH1A1KMT2AKDM4EHPGDMEN1 | |
| SCHEMBL24683226 | 0.77 | PDK1 (0.37) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL29800012 | 0.77 | PDK1 (0.37) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL30701705 | 0.76 | MCL1 (0.39) | KMT2AMEN1CASP3SHBG | |
| SCHEMBL24683876 | 0.76 | MCL1 (0.39) | KMT2AMEN1CASP3SHBG | |
| SCHEMBL29799927 | 0.76 | LMNA (0.38) | KMT2AKDM4EMAPTHPGDMEN1 | |
| SCHEMBL24683205 | 0.76 | LMNA (0.38) | KMT2AKDM4EMAPTHPGDMEN1 | |
| SCHEMBL24683886 | 0.72 | CA12 (0.39) | ALDH1A1NPSR1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |