Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11743887 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Fluoride Ion SCHEMBL2467473 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Iodide SCHEMBL5091418 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Bromide SCHEMBL5092862 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL624283 | 0.85 | ACHE (0.35) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL11022349 | 0.81 | — | — | |
| SCHEMBL11022148 | 0.74 | HTR6 (0.41) | TSHRLMNAALDH1A1TDP1CA4 | |
| Water SCHEMBL11745765 | 0.73 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL63255 | 0.72 | ALDH1A1 (0.38) | TSHRACHELMNAALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10391734 | 0.69 | ALDH1A1 (0.35) | TSHRACHELMNAALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812358-B1 | METHOD OF MANUFACTURING 1-CHLORO-2,3,3-TRIFLUOROPROPENE | AGC INC (JP) | 2023-08-23 | — | — | EP | disclosed |
| EP-4212501-A1 | MIXTURE COMPRISING 2-CHLORO-1,3,3,3-TETRAFLUOROPROPENE AND 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE | AGC INC. (JP) | 2023-07-19 | — | — | EP | disclosed |
| EP-3730471-B1 | METHOD FOR REMOVING 2-CHLORO-1,3,3,3-TETRAFLUOROPROPENE AND METHOD FOR PRODUCING 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE | AGC INC (JP) | 2023-03-22 | — | — | EP | disclosed |
| WO-2021132390-A1 | METHOD FOR PRODUCING 1-CHLORO-2,3,3-TRIFLUOROPROPENE | ＡＧＣ株式会社 | 2021-07-01 | — | — | WO | disclosed |
| US-11046630-B2 | Method for producing 1-chloro-2,3,3,4,4,5,5-heptafluoro-1-pentene, and composition | AGC Inc. (JP) | 2021-06-29 | — | — | US | disclosed |
| EP-3812358-A1 | METHOD OF MANUFACTURING 1-CHLORO-2,3,3-TRIFLUOROPROPENE | AGC INC. (JP) | 2021-04-28 | — | — | EP | disclosed |
| US-20210053896-A1 | METHOD FOR PRODUCING 1-CHLORO-2,3,3,4,4,5,5-HEPTAFLUORO-1-PENTENE, AND COMPOSITION | AGC Inc. (JP) | 2021-02-25 | — | — | US | disclosed |
| EP-3330243-B1 | METHOD FOR PRODUCING 1-CHLORO-2,3,3-TRIFLUOROPROPENE | AGC INC (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-10851034-B2 | Method of removing 2-chloro-1,3,3,3-tetrafluoropropene and method of producing 1-chloro-2,3,3,3-tetrafluoropropene | AGC Inc. (JP) | 2020-12-01 | — | — | US | disclosed |
| EP-3395789-B1 | MANUFACTURING METHOD OF 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE | AGC INC (JP) | 2020-11-18 | — | — | EP | disclosed |
| EP-2218708-A1 | METHOD FOR PRODUCING CARBONATE COMPOUND | Asahi Glass Co., Ltd. (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| US-5055601-A | Epoxidizing fluoroolefin with hypochlorite in basic two phase system containing lipophilic phase transfer catalyst | ASAHI KASEI KOGYO K.K. (JP) | 1991-10-08 | — | — | US | disclosed |
| US-4965379-A | EPOXIDATION OF FLUOROOLEFIN | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1990-10-23 | — | — | US | disclosed |
| US-4925961-A | Epoxidation of hexafluoropropylene | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4902810-A | EPOXIDIZING HEXAFLUOROPROPYLENE; HYPOCHLORITE AS OXIDIZING AGENT | ASAHI KOGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0100488-B1 | FLUOROEPOXIDES AND A PROCESS FOR PRODUCTION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-03-04 | — | — | EP | disclosed |
| EP-0064293-B1 | PROCESS FOR THE PRODUCTION OF HEXAFLUOROPROPYLENE OXIDE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-12-10 | — | — | EP | disclosed |
| EP-0100488-A1 | Fluoroepoxides and a process for production thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-02-15 | — | — | EP | disclosed |
| EP-0064293-A1 | Process for the production of hexafluoropropylene oxide | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046630-B2 | Method for producing 1-chloro-2,3,3,4,4,5,5-heptafluoro-1-pentene, and composition | HTR3C, CTRB2, PUM1 | ACHE 509/4885TSHR 1856/4885LMNA 4541/4885 |
| US-10851034-B2 | Method of removing 2-chloro-1,3,3,3-tetrafluoropropene and method of producing 1-chloro-2,3,3,3-tetrafluoropropene | CPNE4, CCR4, CYP4F2 | ACHE 1399/4885TSHR 847/4885LMNA 3861/4885 |
| US-20210053896-A1 | METHOD FOR PRODUCING 1-CHLORO-2,3,3,4,4,5,5-HEPTAFLUORO-1-PENTENE, AND COMPOSITION | HTR3C, CTRB2, PUM1 | ACHE 509/4885TSHR 1856/4885LMNA 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.