Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 2/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31508067 | 0.91 | CA2 (0.35) | MAP4K4CA2CHKA | |
| SCHEMBL28260875 | 0.74 | NFE2L2 (0.39) | KDM5BKDM5AFEN1HRH4HTR3A | |
| SCHEMBL3468993 | 0.70 | HRH3 (0.38) | KDM5BKDM5AFEN1HRH4CDK2 | |
| SCHEMBL16290873 | 0.70 | CDK2 (0.43) | FEN1CDK2MCHR1 | |
| SCHEMBL21384053 | 0.69 | CYP11B2 (0.39) | FEN1HRH4HTR3AMCHR1HRH3 | |
| SCHEMBL18616362 | 0.68 | CDK2 (0.40) | FEN1HRH4HTR3ACDK2MCHR1 | |
| SCHEMBL20671956 | 0.68 | CDK2 (0.40) | FEN1HRH4HTR3ACDK2MCHR1 | |
| SCHEMBL24692153 | 0.68 | KMO (0.54) | FEN1HRH4PI4KAPI4K2BPI4K2A | |
| SCHEMBL2076056 | 0.68 | KMO (0.54) | FEN1HRH4PI4KAPI4K2BPI4K2A | |
| SCHEMBL28819054 | 0.68 | NFE2L2 (0.44) | FEN1HRH4HTR3AMCHR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256075-A1 | PYRIMIDINE AND PYRIDINE AMINE COMPOUNDS AND USAGE THEREOF IN DISEASE TREATMENT | EPIGEN BIOSCIENCES, INC. (US) | 2022-12-08 | — | — | WO | disclosed |