Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6640497 | 0.83 | KMT2A (0.49) | L3MBTL1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL10022852 | 0.77 | EPHX2 (0.66) | L3MBTL1LMNAKMT2AEPHX2ALDH1A1 | |
| SCHEMBL5204883 | 0.77 | EPHX2 (0.66) | L3MBTL1LMNAKMT2AEPHX2ALDH1A1 | |
| SCHEMBL11012644 | 0.75 | LMNA (0.70) | L3MBTL1LMNAKMT2AEPHX2ALDH1A1 | |
| SCHEMBL27273649 | 0.74 | ALDH1A1 (0.41) | L3MBTL1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL10487443 | 0.74 | KMT2A (0.55) | L3MBTL1LMNAKMT2AEPHX2ALDH1A1 | |
| SCHEMBL25212768 | 0.74 | L3MBTL1 (0.50) | L3MBTL1LMNAKMT2AEPHX2ALDH1A1 | |
| SCHEMBL6716380 | 0.73 | L3MBTL1 (0.60) | L3MBTL1LMNAKMT2AEPHX2ALDH1A1 | |
| SCHEMBL13744595 | 0.73 | KMT2A (0.53) | L3MBTL1LMNAKMT2AEPHX2ALDH1A1 | |
| SCHEMBL29958444 | 0.73 | OGG1 (0.60) | L3MBTL1LMNAKMT2AEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220280509-A1 | AZA-QUINOLINE COMPOUNDS AND USES THEREOF | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2022-09-08 | — | — | US | disclosed |
| CN-114746414-A | Aza-quinoline compounds and uses thereof | 诺华公司 | 2022-07-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220280509-A1 | AZA-QUINOLINE COMPOUNDS AND USES THEREOF | EZH2, BMI1, EED | L3MBTL1 3269/4885LMNA 3624/4885KMT2A 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.