SCHEMBL24701233

SCHEMBL24701233

CCN(c1cccc(-c2ccc(-c3ccccc3N(c3ccccc3)C(C)C)cc2)c1)c1ccc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 4/20 0.36
MAPT P10636 2/20 0.35
HTT P42858 2/20 0.35
MEN1 O00255 1/20 0.35
APAF1 O14727 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
XBP1 P17861 1/20 0.35
PTBP1 P26599 1/20 0.35
RAB9A P51151 1/20 0.35
GALK1 P51570 1/20 0.35
BLM P54132 1/20 0.35
SMAD3 P84022 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23874885 0.84 MAPT (0.43) MAPTHTTMEN1APAF1NPC1
SCHEMBL20203679 0.83 CRHR1 (0.33) CRHR1MAPTHTTMEN1APAF1
SCHEMBL20152511 0.82 MAPT (0.43) MAPTHTTMEN1APAF1NPC1
SCHEMBL21386479 0.79 NR3C1 (0.37) CRHR1MAPTHTTMEN1APAF1
SCHEMBL20152513 0.79 MAPT (0.38) MAPTHTTMEN1APAF1NPC1
SCHEMBL20199430 0.79 MAPT (0.38) MAPTHTTMEN1APAF1NPC1
SCHEMBL23776042 0.79 ALDH1A1 (0.39) MAPTHTTMEN1NPC1LMNA
SCHEMBL23920580 0.78 NPC1 (0.37) MAPTHTTMEN1APAF1NPC1
SCHEMBL16577662 0.76 MAPT (0.39) MAPTNPC1RAB9ASMN1; SMN2NPSR1
SCHEMBL24004252 0.76 MAPT (0.39) MAPTNPC1RAB9ASMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 CRHR1 4826/4885MAPT 3004/4885HTT 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.