SCHEMBL24712723

SCHEMBL24712723

Brc1ccccc1Nc1ccc(C2(c3ccccc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 0.45
▸ MEN1 O00255 6/20 0.45
▸ MAPT P10636 5/20 0.45
▸ LMNA P02545 4/20 0.45
▸ KDM4E B2RXH2 4/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ OPRK1 P41145 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ AURKA O14965 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.36
▸ ESR1 P03372 1/20 0.36
▸ ESR2 Q92731 1/20 0.36
▸ PDK2 Q15119 1/20 0.35
▸ NPC1 O15118 2/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ HTT P42858 1/20 0.34
▸ MAPK14 Q16539 3/20 0.33
▸ GAA P10253 2/20 0.33
▸ GLA P06280 2/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19202306 0.90 PDK2 (0.41) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL26227476 0.83 MEN1 (0.46) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL12745129 0.83 MEN1 (0.49) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL283063 0.82 MAPT (0.55) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL30564983 0.82 MAPT (0.55) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL20871520 0.82 MAPT (0.49) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL15866664 0.80 MAPT (0.57) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL24883319 0.80 MEN1 (0.46) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL1644706 0.79 ALDH1A1 (0.58) KMT2AMEN1MAPTLMNAKDM4E
SCHEMBL30714362 0.79 MEN1 (0.42) KMT2AMEN1MAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230025656-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF CHANGCHUN HYPERIONS TECH CO LTD (CN) 2023-01-26 — — US disclosed
EP-4101841-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF Changchun Hyperions Technology Co., Ltd. (CN) 2022-12-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230025656-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF TRDMT1, TCF4, TRMT1 KMT2A 579/4885MEN1 3248/4885MAPT 647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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