Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20682942 | 0.77 | TSHR (0.46) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL91231 | 0.75 | ADRA2B (0.52) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL18135496 | 0.68 | SLC6A2 (0.44) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL15421785 | 0.67 | SIGMAR1 (0.44) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL15421788 | 0.67 | SIGMAR1 (0.44) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL18079513 | 0.65 | TSHR (0.50) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL8864186 | 0.64 | TSHR (0.45) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL5462061 | 0.64 | TSHR (0.62) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL3635237 | 0.63 | TSHR (0.54) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL608453 | 0.63 | TSHR (0.54) | TSHRALDH1A1SLC6A2SLC6A4ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251018-A1 | PRODUCTION SYSTEM/PRODUCTION PROCESS FOR ACRYLIC ACID AND PRECURSORS THEREOF | NOVOMER, INC. | 2022-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251018-A1 | PRODUCTION SYSTEM/PRODUCTION PROCESS FOR ACRYLIC ACID AND PRECURSORS THEREOF | COASY, ALAD, PCCA | TSHR 4246/4885ALDH1A1 664/4885SLC6A2 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.