Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469145 | 0.84 | ALDH1A1 (0.32) | ALDH1A1MAPTHSD17B10ALOX15HPGD | |
| SCHEMBL6087044 | 0.82 | SMN1; SMN2 (0.37) | ALDH1A1MAPTHSD17B10HPGDMEN1 | |
| SCHEMBL7068458 | 0.79 | — | — | |
| SCHEMBL6086864 | 0.79 | HPGD (0.44) | ALDH1A1MAPTHSD17B10HPGDMAPK1 | |
| SCHEMBL2471874 | 0.79 | MEN1 (0.36) | ALDH1A1MAPTHSD17B10ALOX15HPGD | |
| SCHEMBL6086604 | 0.77 | DRD1 (0.33) | ALDH1A1MAPTHSD17B10HPGDMEN1 | |
| SCHEMBL6086259 | 0.77 | GRIN1 (0.37) | ALDH1A1HSD17B10HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL6085479 | 0.77 | MTNR1A (0.37) | ALDH1A1MAPTHSD17B10HPGDMAPK1 | |
| SCHEMBL6087753 | 0.77 | GRIN1 (0.39) | ALDH1A1HSD17B10HPGDMAPK1MEN1 | |
| SCHEMBL6086132 | 0.77 | TYMS (0.38) | ALDH1A1MAPTHSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986651-B1 | USE OF A PYRIMIDINEDIONE DERIVATIVE FOR PREVENTING OR TREATING HEPATITIS C | SAMJIN PHARM CO LTD (KR) | 2011-10-05 | — | — | EP | claimed |
| US-7851479-B2 | Use of pyrimidinedione derivative for preventing or treating hepatitis C | SAMJIN PHARM. CO., LTD. (KR) | 2010-12-14 | — | — | US | claimed |
| US-20090023764-A1 | Use of Pyrimidinedione Derivative for Preventing or Treating Hepatitis C | SAMJIN PHARM. CO., LTD. (KR) | 2009-01-22 | — | — | US | claimed |
| US-7851479-B2 | Use of pyrimidinedione derivative for preventing or treating hepatitis C | SAMJIN PHARM. CO., LTD. (KR) | 2010-12-14 | — | — | US | disclosed |
| US-7851479-B2 | Use of pyrimidinedione derivative for preventing or treating hepatitis C | SAMJIN PHARM. CO., LTD. (KR) | 2010-12-14 | — | — | US | disclosed |
| US-20090023764-A1 | Use of Pyrimidinedione Derivative for Preventing or Treating Hepatitis C | SAMJIN PHARM. CO., LTD. (KR) | 2009-01-22 | — | — | US | disclosed |
| US-20090023764-A1 | Use of Pyrimidinedione Derivative for Preventing or Treating Hepatitis C | SAMJIN PHARM. CO., LTD. (KR) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023764-A1 | Use of Pyrimidinedione Derivative for Preventing or Treating Hepatitis C | DPYD, UMPS, TYMP | ALDH1A1 186/4885MAPT 4312/4885HSD17B10 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.