Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807750 | 0.80 | CA12 (0.57) | CA12CA1CA2CA9ABCG2 | |
| SCHEMBL2473123 | 0.77 | MAPT (0.47) | MEN1KMT2APDE10AKDM4EALDH1A1 | |
| SCHEMBL7273464 | 0.77 | CA12 (0.54) | CA12CA1CA2CA9ABCG2 | |
| SCHEMBL6800846 | 0.74 | GRM5 (0.54) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL6797398 | 0.73 | ABCG2 (0.56) | CA12CA1CA2CA9ABCG2 | |
| SCHEMBL22575269 | 0.73 | CYP11B2 (0.50) | MEN1KMT2AABCG2GAALMNA | |
| SCHEMBL10549553 | 0.71 | ABCG2 (0.53) | JAK2MEN1KMT2AABCG2JAK3 | |
| SCHEMBL247841 | 0.70 | KDM4E (0.57) | JAK2MEN1KMT2ATRPV4JAK3 | |
| SCHEMBL29624542 | 0.70 | KDM4E (0.57) | JAK2MEN1KMT2ATRPV4JAK3 | |
| Water SCHEMBL6221139 | 0.70 | KDM4E (0.57) | JAK2MEN1KMT2ATRPV4JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254121-A1 | ALKYLAMIDE SUBSTITUTED, ANNULATED IMIDAZOLES AND USE THEREOF AS INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-08-01 | — | — | US | disclosed |
| EP-4334315-A1 | ALKYLAMIDE SUBSTITUTED, ANNULATED IMIDAZOLES AND USE THEREOF AS INSECTICIDES | Bayer Aktiengesellschaft (DE) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022233777-A1 | ALKYLAMIDE SUBSTITUTED, ANNULATED IMIDAZOLES AND USE THEREOF AS INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-11-10 | — | — | WO | disclosed |
| US-8344010-B2 | Fused imidazole derivatives as TRPV3 antagonist | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-01-01 | — | — | US | disclosed |
| US-20110257193-A1 | FUSED IMIDAZOLE DERIVATIVES AS TRPV3 ANTAGONIST | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2011-10-20 | — | — | US | disclosed |
| EP-2370425-A2 | FUSED IMIDAZOLE DERIVATIVES AS TRPV3 ANTAGONIST | Glenmark Pharmaceuticals S.A. (CH) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010073128-A2 | FUSED IMIDAZOLE DERIVATIVES AS TRPV3 ANTAGONIST | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254121-A1 | ALKYLAMIDE SUBSTITUTED, ANNULATED IMIDAZOLES AND USE THEREOF AS INSECTICIDES | AADAC, TAAR1, ARG2 | JAK2 3262/4885CA12 4733/4885CA1 4066/4885 |
| US-20110257193-A1 | FUSED IMIDAZOLE DERIVATIVES AS TRPV3 ANTAGONIST | TRPV3, TRPV1, TRPV2 | JAK2 1992/4885CA12 4475/4885CA1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.