SCHEMBL2472575

SCHEMBL2472575

COc1ccc(C(OCCCOP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 3/20 0.35
SLC6A1 P30531 2/20 0.35
KIF11 P52732 6/20 0.34
KCNH2 Q12809 1/20 0.34
PBRM1 Q86U86 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
GAA P10253 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16329608 0.97 SLC6A1 (0.34) SLC6A11SLC6A1KIF11KCNH2PBRM1
SCHEMBL25764740 0.97 SLC6A1 (0.34) SLC6A11SLC6A1KIF11KCNH2PBRM1
SCHEMBL27050962 0.97 SLC6A1 (0.34) SLC6A11SLC6A1KIF11KCNH2PBRM1
SCHEMBL2820572 0.97 SLC6A1 (0.34) SLC6A11SLC6A1KIF11KCNH2PBRM1
SCHEMBL13930001 0.94 SLC6A11 (0.36) SLC6A11SLC6A1KIF11KCNH2PBRM1
SCHEMBL26996473 0.94 SLC6A1 (0.33) SLC6A11SLC6A1KIF11KCNH2
SCHEMBL26996472 0.93 SLC6A1 (0.33) SLC6A11SLC6A1
SCHEMBL17166451 0.93 ALDH1A1 (0.33) SLC6A11ALDH1A1CYP1A2CYP3A4GAA
SCHEMBL19448739 0.92 SLC6A1 (0.33) SLC6A11SLC6A1
SCHEMBL30802594 0.92 SLC6A1 (0.33) SLC6A11SLC6A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250297258-A1 OLIGONUCLEOTIDE-BASED DELIVERY VEHICLE FOR OLIGONUCLEOTIDES AGENTS AND METHODS OF USE THEREOF RACTIGEN THERAPEUTICS (CN) 2025-09-25 US claimed
EP-2195464-A2 PRIMERS FOR PCR AMPLIFICATION COMPRISING ABASIC PARTS WITHIN THE PRIMER SEQUENCES Bioneer Corporation (KR) 2010-06-16 EP claimed
WO-2009045067-A2 PRIMERS FOR PCR AMPLIFICATION COMPRISING ABASIC PARTS WITHIN THE PRIMER SEQUENCES BIONEER CORPORATION (KR) 2009-04-09 WO claimed
EP-1506399-A2 METHODS AND COMPOSITIONS FOR ANALYZING PROTEINS Aclara BioSciences, Inc. (US) 2005-02-16 EP claimed
WO-2002097112-A2 CATALYTIC AMPLIFICATION OF MULTIPLEXED ASSAY SIGNALS ACLARA BIOSCIENCES, INC. (US) 2002-12-05 WO claimed
WO-2002095356-A2 METHODS AND COMPOSITIONS FOR ANALYZING PROTEINS ACLARA BIOSCIENCES, INC. (US) 2002-11-28 WO claimed
EP-4623082-A1 IN VITRO ENZYMATICAL RNA SYNTHESIS DNA Script (FR) 2025-10-01 EP disclosed
US-20250297258-A1 OLIGONUCLEOTIDE-BASED DELIVERY VEHICLE FOR OLIGONUCLEOTIDES AGENTS AND METHODS OF USE THEREOF RACTIGEN THERAPEUTICS (CN) 2025-09-25 US disclosed
WO-2025042899-A2 METHODS FOR IDENTIFYING COMPOUNDS BINDING TO A TARGET MOLECULE USING MIRROR-IMAGING OF THE TARGET MOLECULE X-CHEM, INC. (US) 2025-02-27 WO disclosed
WO-2024121360-A1 IN VITRO ENZYMATICAL RNA SYNTHESIS DNA SCRIPT (FR) 2024-06-13 WO disclosed
US-20240150824-A1 NUCLEOSIDE-5'-OLIGOPHOSPHATES TAGGED WITH POSTIVIELY-CHARGED POLYMERS, NANOPORES INCORPORATING NEGATIVE CHARGES, AND METHODS AND SYSTEMS USING THE SAME ROCHE SEQUENCING SOLUTIONS INC (US) 2024-05-09 US disclosed
EP-4330397-A1 ANTISENSE-OLIGONUCLEOTIDES FOR PREVENTION OF KIDNEY DYSFUNCTION PROMOTED BY ENDOTHELIAL DYSFUNCTION BY EPHRIN-B2 SUPPRESSION Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-03-06 EP disclosed
EP-4259797-A1 APTAMER-SIRNA FUSIONS Apterna Limited (GB) 2023-10-18 EP disclosed
WO-2001081630-A2 TEMPLATE-SPECIFIC TERMINATION IN A POLYMERASE CHAIN REACTION WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2001-11-01 WO disclosed
WO-2001012787-A2 CHIMERIC DNA/RNA RIBOZYMES CONTAINING PROPANEDIOL CITY OF HOPE (US) 2001-02-22 WO disclosed
EP-1071821-A1 METHODS FOR REDUCING NON-SPECIFIC BINDING TO A NUCLEIC ACID PROBE ARRAY Affymetrix, Inc. (a California Corporation) (US) 2001-01-31 EP disclosed
WO-1999054509-A1 METHODS FOR REDUCING NON-SPECIFIC BINDING TO A NUCLEIC ACID PROBE ARRAY AFFYMETRIX, INC. (US) 1999-10-28 WO disclosed
US-5573906-A Detection of nucleic acids using a hairpin forming oligonucleotide primer and an energy transfer detection system HOFFMANN-LA ROCHE INC. (US) 1996-11-12 US disclosed
EP-0566751-B1 DNA detection method HOFFMANN LA ROCHE (CH) 1996-01-10 EP disclosed
EP-0566751-A1 DNA detection method F. HOFFMANN-LA ROCHE AG (CH) 1993-10-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250297258-A1 OLIGONUCLEOTIDE-BASED DELIVERY VEHICLE FOR OLIGONUCLEOTIDES AGENTS AND METHODS OF USE THEREOF MTREX, DCLRE1B, ADAR SLC6A11 4520/4885SLC6A1 4633/4885KIF11 817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.