Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.74 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | RB1 | P06400 | 2/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146600 | 0.93 | DRD2 (0.71) | DRD2GRIN2BDRD3DRD4RB1 | |
| SCHEMBL5791538 | 0.91 | DRD2 (0.67) | DRD2GRIN2BDRD3DRD4RB1 | |
| Hydrochloric Acid SCHEMBL10447152 | 0.88 | DRD2 (0.61) | DRD2GRIN2BADRA1AACHE | |
| SCHEMBL8074250 | 0.86 | DRD2 (0.83) | DRD2GRIN2BDRD3DRD4 | |
| SCHEMBL8074280 | 0.86 | DRD2 (0.83) | DRD2GRIN2BDRD3DRD4 | |
| SCHEMBL7543711 | 0.86 | DRD2 (0.83) | DRD2GRIN2BDRD3DRD4 | |
| SCHEMBL3320662 | 0.85 | DRD2 (1.00) | DRD2GRIN2BDRD3DRD4CA1 | |
| SCHEMBL15474018 | 0.85 | DRD2 (1.00) | DRD2GRIN2BDRD3DRD4CA1 | |
| Hydrochloric Acid SCHEMBL7932989 | 0.85 | DRD2 (0.81) | DRD2GRIN2BDRD3DRD4 | |
| Hydrochloric Acid SCHEMBL8604442 | 0.85 | DRD2 (0.81) | DRD2GRIN2BDRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282708-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI THERAPEUTICS, INC. (US) | 2025-09-11 | — | — | US | disclosed |
| US-20250282712-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI THERAPEUTICS INC (US) | 2025-09-11 | — | — | US | disclosed |
| US-12351537-B2 | Dimethoxyphenylalkylamine activators of serotonin receptors | ATAI THERAPEUTICS, INC. (US) | 2025-07-08 | — | — | US | disclosed |
| US-12344570-B2 | Aminotetraline activators of serotonin receptors | ATAI THERAPEUTICS, INC. (US) | 2025-07-01 | — | — | US | disclosed |
| US-20240300885-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Life Sciences AG (DE) | 2024-09-12 | — | — | US | disclosed |
| US-20240294461-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. | 2024-09-05 | — | — | US | disclosed |
| US-11926574-B2 | Dimethoxyphenylalkylamine activators of serotonin receptors | Atai Therapeutics Inc. (US) | 2024-03-12 | — | — | US | disclosed |
| CN-117500487-A | Dimethoxy phenyl alkylamine activators of serotonin receptors | 恩泰奥吉尼克斯生物科学公司 | 2024-02-02 | — | — | CN | disclosed |
| US-11827580-B2 | Aminotetraline activators of serotonin receptors | ATAI Life Sciences AG (DE) | 2023-11-28 | — | — | US | disclosed |
| US-11827580-B2 | Aminotetraline activators of serotonin receptors | ATAI Life Sciences AG (DE) | 2023-11-28 | — | — | US | disclosed |
| US-11827580-B2 | Aminotetraline activators of serotonin receptors | ATAI Life Sciences AG (DE) | 2023-11-28 | — | — | US | disclosed |
| WO-2023129909-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Life Sciences AG (DE) | 2023-07-06 | — | — | WO | disclosed |
| US-20230202965-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ENTHEOGENIX BIOSCIENCES, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230202965-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ENTHEOGENIX BIOSCIENCES, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230202965-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ENTHEOGENIX BIOSCIENCES, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. | 2023-05-04 | — | — | US | disclosed |
| WO-2022261240-A2 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Life Sciences AG (DE) | 2022-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300885-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR3B, HTR1B, TAAR5 | DRD2 111/4885GRIN2B 75/4885DRD3 273/4885 |
| US-11926574-B2 | Dimethoxyphenylalkylamine activators of serotonin receptors | HTR1A, HTR7, HTR4 | DRD2 25/4885GRIN2B 249/4885DRD3 57/4885 |
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR1A, HTR7, HTR4 | DRD2 25/4885GRIN2B 249/4885DRD3 57/4885 |
| US-12351537-B2 | Dimethoxyphenylalkylamine activators of serotonin receptors | HTR1A, HTR7, HTR4 | DRD2 25/4885GRIN2B 249/4885DRD3 57/4885 |
| US-20250282708-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR3B, HTR1B, TAAR5 | DRD2 111/4885GRIN2B 75/4885DRD3 273/4885 |
| US-12344570-B2 | Aminotetraline activators of serotonin receptors | HTR3B, HTR1B, TAAR5 | DRD2 111/4885GRIN2B 75/4885DRD3 273/4885 |
| US-11827580-B2 | Aminotetraline activators of serotonin receptors | HTR3B, HTR1B, TAAR5 | DRD2 98/4885GRIN2B 79/4885DRD3 266/4885 |
| US-20250282712-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR1A, HTR7, HTR4 | DRD2 25/4885GRIN2B 249/4885DRD3 57/4885 |
| US-20240294461-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR1A, HTR7, HTR4 | DRD2 25/4885GRIN2B 249/4885DRD3 57/4885 |
| US-20230202965-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR3B, HTR1B, TAAR5 | DRD2 111/4885GRIN2B 75/4885DRD3 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.