Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013490 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KMT2A | |
| SCHEMBL25922429 | 0.79 | DRD2 (0.30) | — | |
| SCHEMBL18800954 | 0.76 | LMNA (0.41) | ALDH1A1KMT2A | |
| SCHEMBL24744823 | 0.75 | — | — | |
| SCHEMBL22297219 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL27798489 | 0.73 | GLB1 (0.39) | — | |
| SCHEMBL23482056 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL24171294 | 0.71 | PRMT3 (0.33) | — | |
| SCHEMBL25706816 | 0.71 | — | — | |
| SCHEMBL24670563 | 0.70 | KDM4E (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |