Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24746198 | 0.92 | RAB9A (0.44) | RAB9ANPC1HSD11B1KMT2AGRM5 | |
| SCHEMBL24746293 | 0.76 | RAB9A (0.44) | RAB9ANPC1HSD11B1KMT2AMEN1 | |
| SCHEMBL7436185 | 0.72 | PIK3CD (0.45) | KMT2AMGLL | |
| SCHEMBL24746206 | 0.72 | NAMPT (0.41) | HSD11B1KMT2AMEN1MGLLGRM5 | |
| SCHEMBL10032955 | 0.72 | SOST (0.34) | RAB9ANPC1HSD11B1KMT2ASOST | |
| SCHEMBL24746289 | 0.71 | HSD11B1 (0.52) | HSD11B1KMT2AMEN1MGLLGRM5 | |
| SCHEMBL548617 | 0.71 | GRIA3 (0.53) | RAB9ANPC1KMT2ASOSTTAS1R3 | |
| SCHEMBL15458881 | 0.69 | RAB9A (0.40) | RAB9ANPC1KMT2AGRM5 | |
| SCHEMBL8403465 | 0.68 | LMNA (0.55) | RAB9A | |
| SCHEMBL25095608 | 0.65 | HSP90AA1 (0.38) | HSD11B1KMT2AMEN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |