Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11775645 | 0.78 | PIK3CD (0.46) | PIK3CDCHRNA7L3MBTL1L3MBTL3ACHE | |
| SCHEMBL7438957 | 0.77 | ALDH1A1 (0.47) | PIK3CDCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL11777276 | 0.77 | CHRNB2 (0.46) | PIK3CDCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL7438099 | 0.76 | ABCB1 (0.43) | PIK3CDCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10635857 | 0.76 | PIK3CD (0.47) | PIK3CDCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4030570 | 0.74 | CHRNA7 (0.60) | CHRNA3CHRNA7L3MBTL1L3MBTL3ACHE | |
| SCHEMBL27348973 | 0.73 | PIK3CD (0.50) | PIK3CDCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL252505 | 0.73 | ACHE (0.55) | PIK3CDCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL24746302 | 0.72 | RAB9A (0.36) | KMT2AMGLL | |
| SCHEMBL10032955 | 0.72 | SOST (0.34) | CHRNA7L3MBTL1L3MBTL3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240935-A | Central nervous system disorders | STERLING WINTHROP INC. (US) | 1993-08-31 | — | — | US | disclosed |