Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17209800 | 0.81 | BCL6 (0.51) | NUDT1L3MBTL1NLRP3PGK1BCL6 | |
| SCHEMBL1801013 | 0.81 | LMNA (0.39) | L3MBTL1MAPK8PGK1 | |
| SCHEMBL12639125 | 0.78 | ALDH1A1 (0.39) | MAPK8PGK1KDM4E | |
| SCHEMBL3159641 | 0.77 | NUDT1 (0.43) | NUDT1L3MBTL1HRH4KDM4E | |
| SCHEMBL16011451 | 0.77 | NUDT1 (0.42) | NUDT1L3MBTL1HRH4BCL6 | |
| SCHEMBL29582290 | 0.77 | NUDT1 (0.47) | NUDT1 | |
| SCHEMBL21346508 | 0.72 | KDM4E (0.41) | MAPK8PGK1KDM4E | |
| SCHEMBL5518128 | 0.71 | CDK4 (0.45) | — | |
| SCHEMBL23392698 | 0.71 | APP (0.59) | — | |
| SCHEMBL11578567 | 0.69 | NLRP3 (0.43) | L3MBTL1NLRP3MAPK8PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262784-A1 | IDH MUTANT INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2022-12-22 | — | — | WO | disclosed |