Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472667 | 0.78 | TNF (0.49) | NUDT1L3MBTL1TNF | |
| SCHEMBL24765256 | 0.77 | NUDT1 (0.46) | NUDT1KDM4EL3MBTL1HRH4 | |
| SCHEMBL3162598 | 0.76 | L3MBTL1 (0.71) | L3MBTL1POLBALDH1A1GAACYP3A4 | |
| SCHEMBL3251723 | 0.72 | KDM4E (0.45) | KDM4EMAPK1CHUKCYP2C19CCNA2 | |
| SCHEMBL7521450 | 0.71 | RXFP1 (0.56) | KDM4EMAPK1CYP2D6CYP2C19EGFR | |
| SCHEMBL5205294 | 0.71 | MMP13 (0.40) | NUDT1KDM4EALDH1A1TNF | |
| SCHEMBL5205013 | 0.71 | KCNH2 (0.40) | KDM4ECYP2D6CYP2C19POLBALDH1A1 | |
| SCHEMBL5206828 | 0.71 | MAPT (0.39) | KDM4EMAPK1L3MBTL1ALDH1A1TNF | |
| SCHEMBL3252539 | 0.70 | NPC1 (0.38) | NUDT1KDM4EMAPK1CHUKCYP2D6 | |
| SCHEMBL3253939 | 0.70 | IRAK1 (0.41) | KDM4EMAPK1CHUKCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883639-B1 | PREPARATION OF FAMCICLOVIR AND OTHER PURINE DERIVATIVES | ARROW INT LTD (MT) | 2010-09-01 | — | — | EP | disclosed |
| EP-1636231-B1 | METHODS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE USING A COMPOUND OF 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES | KYUNGDONG PHARM CO LTD (KR) | 2010-03-24 | — | — | EP | disclosed |
| US-7601835-B2 | Preparation of famciclovir and other purine derivatives | ARROW INTERNATIONAL LIMITED (MT) | 2009-10-13 | — | — | US | disclosed |
| US-7601835-B2 | Preparation of famciclovir and other purine derivatives | ARROW INTERNATIONAL LIMITED (MT) | 2009-10-13 | — | — | US | disclosed |
| CN-100455583-C | 2-amino-9- (2-substituted ethyl) purines and methods of using same to prepare 9- [ 4-acetoxy-3- (acetoxymethyl) butan-1-yl ] -2-aminopurine | KYUNGDONG PHARM CO LTD (KR) | 2009-01-28 | — | — | CN | disclosed |
| US-7456282-B2 | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2008-11-25 | — | — | US | disclosed |
| US-7456282-B2 | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2008-11-25 | — | — | US | disclosed |
| US-7456282-B2 | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2008-11-25 | — | — | US | disclosed |
| US-20060258862-A1 | 2-Amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2006-11-16 | — | — | US | disclosed |
| CN-1791602-A | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9- 4-acetoxy-3-(acetoxymethyl)but-1-yl]- 2- aminopurine using the same | KYUNGDONG PHARM CO LTD (KR) | 2006-06-21 | — | — | CN | disclosed |
| EP-1636231-A2 | 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES AND PREPARING METHODS FOR 9- 4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]- 2- AMINOPURINE USING THE SAME | Kyungdong Pharm. Co., Ltd. (KR) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110343-A2 | 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES AND PREPARING METHODS FOR 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]- 2- AMINOPURINE USING THE SAME | KYUNGDONG PHARM. CO., LTD. (KR) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258862-A1 | 2-Amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | TYMP, TPMT, PNP | NUDT1 7/4885KDM4E 783/4885MAPK1 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.