SCHEMBL2476750

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2473883	0.93	TSHR (0.57)	USP2TSHRMAPTMEN1KMT2A
	SCHEMBL2478906	0.91	KDM1A (0.45)	USP2TSHRMAPTMEN1KMT2A
	SCHEMBL4219614	0.89	USP2 (0.55)	USP2TSHRMAPTMEN1KMT2A
	SCHEMBL2478980	0.89	USP2 (0.52)	USP2TSHRMAPTMEN1KMT2A
	SCHEMBL2476317	0.88	TSHR (0.53)	USP2TSHRMAPTALDH1A1GAA
	SCHEMBL2478152	0.87	HDAC1 (0.55)	USP2TSHRMAPTMEN1KMT2A
	SCHEMBL2476477	0.86	USP2 (0.54)	USP2TSHRMAPTMEN1KMT2A
	SCHEMBL2478994	0.85	HDAC1 (0.54)	HDAC1
	SCHEMBL2477252	0.85	TSHR (0.64)	USP2TSHRMAPTMEN1KMT2A
	SCHEMBL2476586	0.85	HSD17B10 (0.55)	TSHRMAPTALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.