SCHEMBL2478152

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2470965	0.92	OPRM1 (0.53)	HDAC1HDAC6TSHRMAPTHSD17B10
	SCHEMBL2473883	0.89	TSHR (0.57)	HDAC1CASRTSHRMAPTHSD17B10
	SCHEMBL2497298	0.88	HDAC1 (0.52)	HDAC1HDAC6CASRTSHRMAPT
	SCHEMBL2476750	0.87	USP2 (0.54)	HDAC1CASRTSHRMAPTHSD17B10
	SCHEMBL2476586	0.87	HSD17B10 (0.55)	HDAC1HDAC6TSHRMAPTHSD17B10
	SCHEMBL2477045	0.87	POLB (0.51)	HDAC1HDAC6CASRTSHRMAPT
	SCHEMBL2477106	0.87	OPRM1 (0.54)	HDAC1HDAC6TSHRMAPTHSD17B10
	SCHEMBL2475852	0.86	OPRM1 (0.53)	HDAC1HDAC6TSHRMAPTHSD17B10
	SCHEMBL2473792	0.86	ALDH1A1 (0.54)	HDAC1TSHRMAPTHSD17B10ALDH1A1
	SCHEMBL2473980	0.86	ALDH1A1 (0.54)	HDAC1TSHRMAPTHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.