Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16217224 | 0.81 | MAPT (0.54) | MAPTPOLBALDH1A1HSD11B1GAA | |
| SCHEMBL12883301 | 0.76 | MAPT (0.52) | MAPTPOLBALDH1A1HSD11B1GAA | |
| SCHEMBL975710 | 0.74 | MAPT (0.60) | MAPTPOLBALDH1A1HSD11B1GAA | |
| SCHEMBL14269337 | 0.74 | MAPT (0.56) | MAPTPOLBALDH1A1HSD11B1GAA | |
| SCHEMBL2145779 | 0.74 | ALDH1A1 (0.54) | MAPTPOLBALDH1A1GAAKDM4E | |
| SCHEMBL2199155 | 0.73 | MAPT (0.56) | MAPTPOLBALDH1A1HSD11B1GAA | |
| SCHEMBL5206178 | 0.73 | MAPT (0.55) | MAPTPOLBALDH1A1HSD11B1GAA | |
| SCHEMBL13544346 | 0.70 | MAPT (0.52) | MAPTPOLBALDH1A1HSD11B1GAA | |
| SCHEMBL7988803 | 0.70 | MAPT (0.52) | MAPTPOLBALDH1A1HSD11B1GAA | |
| SCHEMBL15312202 | 0.69 | GAA (0.43) | MAPTPOLBALDH1A1HSD11B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220400678-A1 | OXIME ETHER COMPOUND AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220400678-A1 | OXIME ETHER COMPOUND AND APPLICATION THEREOF | CYP2E1, GALE, OGFOD1 | MAPT 3703/4885POLB 2611/4885ALDH1A1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.