Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481726 | 0.84 | NR3C2 (0.78) | NR3C1NR3C2KEAP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28394019 | 0.84 | NR3C1 (0.59) | NR3C1NR3C2KEAP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27183050 | 0.82 | ALDH1A1 (0.47) | NR3C1ALDH1A1SMN1; SMN2MAPK1ALOX15 | |
| SCHEMBL698855 | 0.82 | KEAP1 (0.70) | NR3C1NR3C2KEAP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5945125 | 0.81 | NR3C1 (0.68) | NR3C1NR3C2KEAP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29407201 | 0.81 | NR3C1 (0.68) | NR3C1NR3C2KEAP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7024769 | 0.80 | NR3C2 (0.58) | NR3C1NR3C2KEAP1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11059615 | 0.80 | NR3C1 (0.67) | NR3C1NR3C2KEAP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7528456 | 0.80 | CA2 (0.56) | NR3C1ALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL28974174 | 0.78 | NR3C1 (0.65) | NR3C1NR3C2KEAP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5718731-A | Oxidation hair dye composition based on 4,5-diaminopyrazole and m-phenylenediamine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | claimed |
| EP-0692245-B1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | WELLA AG (DE) | 1997-05-02 | — | — | EP | claimed |
| EP-0692245-A1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | Wella Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | claimed |
| EP-4327874-A2 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | WisTa Laboratories Ltd. (SG) | 2024-02-28 | — | — | EP | disclosed |
| EP-3689346-B1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS FOR TREATING TAUOPATHIES | WISTA LAB LTD (SG) | 2024-01-24 | — | — | EP | disclosed |
| EP-3689346-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | WisTa Laboratories Ltd. (SG) | 2020-08-05 | — | — | EP | disclosed |
| EP-3112358-B1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | WISTA LAB LTD (SG) | 2020-04-29 | — | — | EP | disclosed |
| US-10399955-B2 | 3,6-disubstituted xanthylium salts | WISTA LABORATORIES LTD. (SG) | 2019-09-03 | — | — | US | disclosed |
| US-20170088534-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | WISTA LABORATORIES LTD. (SG) | 2017-03-30 | — | — | US | disclosed |
| US-20170088534-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | WISTA LABORATORIES LTD. (SG) | 2017-03-30 | — | — | US | disclosed |
| US-9549933-B2 | 3,6-disubstituted xanthylium salts | WISTA LABORATORIES LTD. (SG) | 2017-01-24 | — | — | US | disclosed |
| US-20110300074-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | WISTA LABORATORIES LTD. (SG) | 2011-12-08 | — | — | US | disclosed |
| US-20110300074-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | WISTA LABORATORIES LTD. (SG) | 2011-12-08 | — | — | US | disclosed |
| EP-2373660-A2 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS AS MEDICAMENTS | Wista Laboratories Ltd. (SG) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010067078-A2 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS AS MEDICAMENTS | WISTA LABORATORIES LTD. (SG) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010067078-A2 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS AS MEDICAMENTS | WISTA LABORATORIES LTD. (SG) | 2010-06-17 | — | — | WO | disclosed |
| US-5718731-A | Oxidation hair dye composition based on 4,5-diaminopyrazole and m-phenylenediamine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| US-5718731-A | Oxidation hair dye composition based on 4,5-diaminopyrazole and m-phenylenediamine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| EP-0692245-B1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | WELLA AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| EP-0692245-A1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | Wella Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399955-B2 | 3,6-disubstituted xanthylium salts | MAPT, PSEN2, PSEN1 | NR3C1 3471/4885NR3C2 2983/4885KEAP1 251/4885 |
| US-20170088534-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | MAPT, PSEN2, PSEN1 | NR3C1 3471/4885NR3C2 2983/4885KEAP1 251/4885 |
| US-20110300074-A1 | 3,6-DISUBSTITUTED XANTHYLIUM SALTS | MAPT, PSEN2, PSEN1 | NR3C1 2468/4885NR3C2 1543/4885KEAP1 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.