SCHEMBL24774255 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	LTA4H	P09960	3/20	0.49

▸	KLKB1	P03952	1/20	0.47

▸	SPHK1	Q9NYA1	2/20	0.45

▸	PDF	Q9HBH1	1/20	0.42

▸	SSTR3	P32745	1/20	0.42

▸	HDAC2	Q92769	1/20	0.41

▸	PLG	P00747	1/20	0.40

▸	SIRT1	Q96EB6	4/20	0.39

▸	SIRT2	Q8IXJ6	3/20	0.39

▸	LNPEP	Q9UIQ6	2/20	0.39

▸	CA1	P00915	2/20	0.39

▸	CA2	P00918	2/20	0.39

▸	EPOR	P19235	1/20	0.39

▸	MMP3	P08254	1/20	0.39

▸	ERAP2	Q6P179	1/20	0.38

▸	SIRT3	Q9NTG7	2/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21726052	0.88	CA1 (0.51)	LTA4HKLKB1PDFSSTR3PLG
SCHEMBL16418621	0.87	KLKB1 (0.49)	LTA4HKLKB1PDFSSTR3HDAC2
SCHEMBL17424310	0.86	SPHK1 (0.51)	LTA4HKLKB1SPHK1PDFSSTR3
SCHEMBL16479322	0.83	SSTR3 (0.53)	LTA4HSSTR3SIRT1SIRT2MMP3
SCHEMBL15810600	0.80	KLKB1 (0.43)	LTA4HKLKB1SPHK1PDFSSTR3
SCHEMBL24774073	0.80	KLKB1 (0.44)	LTA4HKLKB1PDFSSTR3HDAC2
SCHEMBL13411054	0.78	SSTR3 (0.60)	LTA4HSSTR3MMP3
SCHEMBL16645118	0.77	FURIN (0.47)	LTA4HKLKB1PDFSSTR3PLG
SCHEMBL14821040	0.76	SSTR3 (0.55)	LTA4HSSTR3SIRT1SIRT2MMP3
SCHEMBL14872058	0.76	SSTR3 (0.55)	LTA4HSSTR3SIRT1SIRT2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022253033-A1	CHEMICAL COUPLING LINKER AND USE THEREOF	四川科伦博泰生物医药股份有限公司	2022-12-08	—	—	WO	disclosed